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Comparison the effects of carotid endarterectomy with carotid artery stenting for contralateral carotid occlusion

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  • Yaxuan Sun
  • Yongxia Ding
  • Kun Meng
  • Bin Han
  • Jing Wang
  • Yan Han

Abstract

Background: There have been inconsistent results regarding the use of carotid artery endarterectomy (CEA) versus carotid artery stenting (CAS) for contralateral carotid occlusion (CCO). This study aimed to determine the optimal revascularization technique for patients with CCO. Methods: We systematically searched the PubMed, Embase, and Cochrane Library databases to identify eligible studies published from inception to January 2, 2021. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to calculate pooled effect estimates using a random-effects model. Sensitivity, subgroup, and publication bias analyses were also performed. Results: Six studies involving 6,953 patients were selected for inclusion in this meta-analysis. Our results showed that while CEA was not associated with an increased risk of stroke compared to CAS (OR: 1.07; 95% CI: 0.75–1.51; P = 0.713), CEA was associated with a reduced risk of death compared to CAS (OR: 0.45; 95% CI: 0.29–0.70; P

Suggested Citation

  • Yaxuan Sun & Yongxia Ding & Kun Meng & Bin Han & Jing Wang & Yan Han, 2021. "Comparison the effects of carotid endarterectomy with carotid artery stenting for contralateral carotid occlusion," PLOS ONE, Public Library of Science, vol. 16(5), pages 1-13, May.
    • Handle: RePEc:plo:pone00:0250580
    DOI: 10.1371/journal.pone.0250580
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    2. Aurelio Tobias, 1999. "Assessing the influence of a single study in the meta-anyalysis estimate," Stata Technical Bulletin, StataCorp LLC, vol. 8(47).
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