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Prevalence and characteristics of fever in adult and paediatric patients with coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis of 17515 patients

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  • Md Asiful Islam
  • Shoumik Kundu
  • Sayeda Sadia Alam
  • Tareq Hossan
  • Mohammad Amjad Kamal
  • Rosline Hassan

Abstract

Background: Coronavirus disease 2019 (COVID-19), a pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 started to spread globally since December 2019 from Wuhan, China. Fever has been observed as one of the most common clinical manifestations, although the prevalence and characteristics of fever in adult and paediatric COVID-19 patients is inconclusive. We aimed to conduct a systematic review and meta-analysis to estimate the overall pooled prevalence of fever and chills in addition to fever characteristics (low, medium, and high temperature) in both adult and paediatric COVID-19 patients. Methods: The protocol of this systematic review and meta-analysis was registered with PROSPERO (CRD42020176327). PubMed, Scopus, ScienceDirect and Google Scholar databases were searched between 1st December 2019 and 3rd April 2020 without language restrictions. Both adult (≥18 years) and paediatric (

Suggested Citation

  • Md Asiful Islam & Shoumik Kundu & Sayeda Sadia Alam & Tareq Hossan & Mohammad Amjad Kamal & Rosline Hassan, 2021. "Prevalence and characteristics of fever in adult and paediatric patients with coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis of 17515 patients," PLOS ONE, Public Library of Science, vol. 16(4), pages 1-21, April.
    • Handle: RePEc:plo:pone00:0249788
    DOI: 10.1371/journal.pone.0249788
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    1. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    2. Viechtbauer, Wolfgang, 2010. "Conducting Meta-Analyses in R with the metafor Package," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 36(i03).
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    1. Jan Schmidt & Eliska Waldova & Stepanka Balkova & Jakub Suchanek & Roman Smucler, 2021. "Impact of COVID-19 on Czech Dentistry: A Nationwide Cross-Sectional Preliminary Study among Dentists in the Czech Republic," IJERPH, MDPI, vol. 18(17), pages 1-14, August.
    2. Chayu Yang & Bo Deng, 2024. "Dynamics of Infectious Diseases Incorporating a Testing Compartment," Mathematics, MDPI, vol. 12(12), pages 1-18, June.

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