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Evaluating access to oral anti-diabetic medicines: A cross-sectional survey of prices, availability and affordability in Shaanxi Province, Western China

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  • Caijun Yang
  • Shuchen Hu
  • Yanbing Zhu
  • Wenwen Zhu
  • Zongjie Li
  • Yu Fang

Abstract

Objectives: To assess the availability and affordability of oral anti-diabetic medicines in Shaanxi Province, Western China. Methods: In 2015, the prices and availability of 8 anti-diabetic medicines covering 31 different dosage forms and strengths were collected in six cities of Shaanxi Province. A total of 72 public hospitals and 72 private pharmacies were sampled, using a modified methodology developed by the World Health Organization (WHO) and Health Action International (HAI). Medicine prices were compared with international reference prices to obtain a median price ratio. For urban residents, affordability was assessed as the lowest-paid unskilled government workers to purchase cost of standard treatment in days’ wages; for rural residents, days’ net income was used. Results: The mean availabilities of originator brands (OBs) and generics were 34.3% and 28.7% in public hospitals, and 44.1% and 64.4% in the private pharmacies. OBs and the lowest priced generics (LPGs) were procured at 12.38 and 4.52 times the international reference price in public hospitals, and 10.26 and 2.81 times the international reference prices in private pharmacies. Treatments with OBs were unaffordable even for urban residents. The affordability of the LPGs was good, except for acarbose, repaglinide and pioglitazone. Conclusions: Most anti-diabetic medicines cannot met the WHO’s availability target (80% availability) in Shaanxi Province. The high prices of OBs had severely influenced the affordability of medicines, especially for the rural residents. Effective policies should be initiated to ensure the Chinese people a better access to more affordable anti-diabetic medicines.

Suggested Citation

  • Caijun Yang & Shuchen Hu & Yanbing Zhu & Wenwen Zhu & Zongjie Li & Yu Fang, 2019. "Evaluating access to oral anti-diabetic medicines: A cross-sectional survey of prices, availability and affordability in Shaanxi Province, Western China," PLOS ONE, Public Library of Science, vol. 14(10), pages 1-13, October.
  • Handle: RePEc:plo:pone00:0223769
    DOI: 10.1371/journal.pone.0223769
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    References listed on IDEAS

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    1. Xiao Wang & Yu Fang & Shimin Yang & Minghuan Jiang & Kangkang Yan & Lina Wu & Bing Lv & Qian Shen, 2014. "Access to Paediatric Essential Medicines: A Survey of Prices, Availability, Affordability and Price Components in Shaanxi Province, China," PLOS ONE, Public Library of Science, vol. 9(3), pages 1-7, March.
    2. Kankeu Tchewonpi, Hyacinthe & Saksena, Priyanka & Xu, Ke & Evans, David B, 2013. "The financial burden from non-communicable diseases in low- and middle-income countries: a literature review," MPRA Paper 54534, University Library of Munich, Germany.
    3. Minghuan Jiang & Shimin Yang & Kangkang Yan & Jun Liu & Jun Zhao & Yu Fang, 2013. "Measuring Access to Medicines: A Survey of Prices, Availability and Affordability in Shaanxi Province of China," PLOS ONE, Public Library of Science, vol. 8(8), pages 1-8, August.
    4. Margaret Ewen & Marjolein Zweekhorst & Barbara Regeer & Richard Laing, 2017. "Baseline assessment of WHO’s target for both availability and affordability of essential medicines to treat non-communicable diseases," PLOS ONE, Public Library of Science, vol. 12(2), pages 1-13, February.
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    1. Krizzia Lambojon & Jie Chang & Amna Saeed & Khezar Hayat & Pengchao Li & Minghuan Jiang & Naveel Atif & Gebrehaweria Kassa Desalegn & Faiz Ullah Khan & Yu Fang, 2020. "Prices, Availability and Affordability of Medicines with Value-Added Tax Exemption: A Cross-Sectional Survey in the Philippines," IJERPH, MDPI, vol. 17(14), pages 1-15, July.
    2. Leila Zarei & Iman Karimzadeh & Najmeh Moradi & Payam Peymani & Sara Asadi & Zaheer-Ud-Din Babar, 2020. "Affordability Assessment from a Static to Dynamic Concept: A Scenario-Based Assessment of Cardiovascular Medicines," IJERPH, MDPI, vol. 17(5), pages 1-19, March.

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