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Prevalence and determinants of antenatal depression in Ethiopia: A systematic review and meta-analysis

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  • Getinet Ayano
  • Getachew Tesfaw
  • Shegaye Shumet

Abstract

Background: Maternal depression is the most prevalent psychiatric disorder during pregnancy, can alter fetal development and have a lasting impact on the offspring's neurological and behavioral development. However, no review has been conducted to report the consolidated magnitude of antenatal depression (AND) in Ethiopia. Therefore, this review aimed to systematically summarize the existing evidence on the epidemiology of AND in Ethiopia. Methods: Using PRISMA guideline, we systematically reviewed and meta-analyzed studies that examined the prevalence and associated factors of AND from three electronic databases (PubMed, EMBASE, and SCOPUS). We used predefined inclusion criteria to screen identified studies. A qualitative and quantitative analysis was employed. Heterogeneity across the studies was evaluated using Q and the I² test. Publication bias was assessed by funnel plot and Egger’s regression test. Results: In this review, a total of 193 studies were initially identified and evaluated. Of these, five eligible articles were included in the final analysis. In our meta-analysis, the pooled prevalence of AND in Ethiopia was 21.28% (95% CI; 15.96–27.78). The prevalence of AND was highest in the third trimester of pregnancy at 32.10% and it was 19.13% in the first trimester and 18.86% in the second trimester of pregnancy. The prevalence of AND was 26.48% and 18.28% as measured by Beck depression inventory (BDI) and the Edinburgh Postnatal Depression Scale (EPDS), respectively. Moreover, the prevalence of AND was 15.50% for the studies conducted in the community setting and it was 25.77% for the studies conducted in the institution-based setting. In our qualitative synthesis, we found that those pregnant women who had a history of stillbirth, complications during pregnancy, previous history of depression, no ANC follow-up, irregular ANC follow-up, not satisfied by ANC follow-up, and monthly income

Suggested Citation

  • Getinet Ayano & Getachew Tesfaw & Shegaye Shumet, 2019. "Prevalence and determinants of antenatal depression in Ethiopia: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 14(2), pages 1-17, February.
    • Handle: RePEc:plo:pone00:0211764
    DOI: 10.1371/journal.pone.0211764
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    References listed on IDEAS

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    1. Telake Azale Bisetegn & Getnet Mihretie & Tefera Muche, 2016. "Prevalence and Predictors of Depression among Pregnant Women in Debretabor Town, Northwest Ethiopia," PLOS ONE, Public Library of Science, vol. 11(9), pages 1-10, September.
    2. Colin D Mathers & Dejan Loncar, 2006. "Projections of Global Mortality and Burden of Disease from 2002 to 2030," PLOS Medicine, Public Library of Science, vol. 3(11), pages 1-20, November.
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