IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0204286.html
   My bibliography  Save this article

Forensic characterization and genetic polymorphisms of 19 X-chromosomal STRs in 1344 Han Chinese individuals and comprehensive population relationship analyses among 20 Chinese groups

Author

Listed:
  • Pengyu Chen
  • Guanglin He
  • Xing Zou
  • Mengge Wang
  • Fuquan Jia
  • Huiru Bai
  • Jida Li
  • Jian Yu
  • Yanyan Han

Abstract

X-chromosomal short tandem repeats (X-STRs) may assist resolution of complex forensic kinship cases and complement autosomal and Y-chromosomal STRs in routine forensic practice and population genetics. In the present study, we investigated the allele/haplotype diversity and forensic genetic characteristics of 19 X- STRs in 206 Guizhou Han and 1344 Meta-Han Chinese individuals using AGCU X19 PCR amplification system. Population relationships within five Han Chinese population groups (1344 individuals), between Guizhou Han and other 19 Chinese reference populations belonging to four language families (5074 individuals), as well as between Meta-Han Chinese and other 15 minorities (3730 individuals) were performed using Reynolds’s, Nei’s and Fst genetic distances, principal component analysis (PCA), multidimensional scaling (MDS), Structure and Neighbor-Joining tree. Mean paternity exclusion chance (MEC) in Duos > 0.99999999453588 and in trios > 0.99999999999781, as well as power of discrimination (PD) > 0.99999999999980 in Guizhou Han on the basis of allele frequencies. Consistent high MECs and PDs can be observed in Meta-Han Chinese population based on both allele diversities of 19 markers and haplotype diversities of seven linkage groups (LG). DXS10135 and LG1 are the most informative and polymorphic in Han Chinese group. The comprehensive population comparisons reveal that Han Chinese is a homogenous population and has the genetically closer relationship with Hmong-Mien-speaking groups than Tibetan-Burman-speaking and Turkic-speaking populations. In summary, AGCU X19 PCR amplification system is highly polymorphic and informative in Guizhou Han and Han Chinese populations. The comprehensive population data from 20 Chinese populations analyzed in this study may be used as a reference Chinese frequency database of X-STRs for forensic casework applications.

Suggested Citation

  • Pengyu Chen & Guanglin He & Xing Zou & Mengge Wang & Fuquan Jia & Huiru Bai & Jida Li & Jian Yu & Yanyan Han, 2018. "Forensic characterization and genetic polymorphisms of 19 X-chromosomal STRs in 1344 Han Chinese individuals and comprehensive population relationship analyses among 20 Chinese groups," PLOS ONE, Public Library of Science, vol. 13(9), pages 1-21, September.
    • Handle: RePEc:plo:pone00:0204286
    DOI: 10.1371/journal.pone.0204286
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204286
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0204286&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0204286?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Sergei M. Mirkin, 2007. "Expandable DNA repeats and human disease," Nature, Nature, vol. 447(7147), pages 932-940, June.
    2. Chi Zhang, 2017. "Population in China," Europe-Asia Studies, Taylor & Francis Journals, vol. 69(8), pages 1333-1334, September.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Ordoñez, Pablo J., 2020. "Power Plants, Air Pollution, and Health in Colombia," 2020 Annual Meeting, July 26-28, Kansas City, Missouri 304284, Agricultural and Applied Economics Association.
    2. Jia Zhang & Xiaoshu Chen & Shiwei Huang & Yi Wang & Wei Lin & Rui Zhou & He Zou, 2018. "Two-minute walk test: Reference equations for healthy adults in China," PLOS ONE, Public Library of Science, vol. 13(8), pages 1-10, August.
    3. Zhongqiang Bai & Juanle Wang & Mingming Wang & Mengxu Gao & Jiulin Sun, 2018. "Accuracy Assessment of Multi-Source Gridded Population Distribution Datasets in China," Sustainability, MDPI, vol. 10(5), pages 1-15, April.
    4. Zhen Wang & Mingzhi Hu & Yu Zhang & Zhuo Chen, 2022. "Housing Security and Settlement Intentions of Migrants in Urban China," IJERPH, MDPI, vol. 19(16), pages 1-16, August.
    5. Yanjun Yang & Rui Xue & Dong Yang, 2020. "Does market segmentation necessarily discourage energy efficiency?," PLOS ONE, Public Library of Science, vol. 15(5), pages 1-19, May.
    6. Yishu, Li, 2019. "A photovoltaic ecosystem: improving atmospheric environment and fighting regional poverty," Technological Forecasting and Social Change, Elsevier, vol. 140(C), pages 69-79.
    7. Wen Liu & Guosheng Han & Xiangzi Yan & Xuan Zhang & Guangjie Ning & Armigon Ravshanovich Akhmedov & William Cannon Hunter, 2021. "The Impact of Mental Health Status on Health Consumption of the Elderly in China," IJERPH, MDPI, vol. 18(12), pages 1-17, June.
    8. Huimin Du & Jing Song & Si-ming Li, 2021. "‘Peasants are peasants’: Prejudice against displaced villagers in newly-built urban neighbourhoods in China," Urban Studies, Urban Studies Journal Limited, vol. 58(8), pages 1598-1614, June.
    9. Luyao Wang & Hong Fan & Yankun Wang, 2018. "Estimation of consumption potentiality using VIIRS night-time light data," PLOS ONE, Public Library of Science, vol. 13(10), pages 1-19, October.
    10. Ling Zhang & Xiaodong Tan, 2021. "Educational Assortative Mating and Health: A Study in Chinese Internal Migrants," IJERPH, MDPI, vol. 18(4), pages 1-14, February.
    11. Bin Du & Ying Wang & Jiaxin He & Wai Li & Xiaohong Chen, 2021. "Spatio-Temporal Characteristics and Obstacle Factors of the Urban-Rural Integration of China’s Shrinking Cities in the Context of Sustainable Development," Sustainability, MDPI, vol. 13(8), pages 1-16, April.
    12. Dianxi Wang & Yufeng Zhao, 2021. "A potential new pattern of pathway to adulthood is emerging in China," Demographic Research, Max Planck Institute for Demographic Research, Rostock, Germany, vol. 44(42), pages 1023-1056.
    13. JIANG, Qijun & FLORKOWSKI, Wojciech Jan, 2021. "Factors Limiting Quality Assurance Program Implementation In Food Manufacturing Companies In Shanghai, China," Review of Agricultural and Applied Economics (RAAE), Faculty of Economics and Management, Slovak Agricultural University in Nitra, vol. 24(01), March.
    14. Jinjing Wu & Shelby Deaton & Boshen Jiao & Zohn Rosen & Peter A Muennig, 2018. "The cost-effectiveness analysis of the New Rural Cooperative Medical Scheme in China," PLOS ONE, Public Library of Science, vol. 13(12), pages 1-13, December.
    15. Xin Lao & Hengyu Gu, 2020. "Unveiling various spatial patterns of determinants of hukou transfer intentions in China: A multi‐scale geographically weighted regression approach," Growth and Change, Wiley Blackwell, vol. 51(4), pages 1860-1876, December.
    16. Youliang Jin & Chen Cheng & Huixiang Zeng, 2020. "Is evil rewarded with evil? The market penalty effect of corporate environmentally irresponsible events," Business Strategy and the Environment, Wiley Blackwell, vol. 29(3), pages 846-871, March.
    17. Zhishan Ma & Susu Zhang & Sidong Zhao, 2021. "Study on the Spatial Pattern of Migration Population in Egypt and Its Flow Field Characteristics from the Perspective of “Source-Flow-Sink”," Sustainability, MDPI, vol. 13(1), pages 1-27, January.
    18. Jin Liu & Bingdong Hou & Xiao-Wei Ma & Hua Liao, 2018. "Solid fuel use for cooking and its health effects on the elderly in rural China," CEEP-BIT Working Papers 111, Center for Energy and Environmental Policy Research (CEEP), Beijing Institute of Technology.
    19. Jaqueson K. Galimberti, 2020. "Forecasting GDP Growth from Outer Space," Oxford Bulletin of Economics and Statistics, Department of Economics, University of Oxford, vol. 82(4), pages 697-722, August.
    20. Mengkai Chen & Yidong Wu & Guiwen Liu & Xianzhu Wang, 2020. "City economic development, housing availability, and migrants' settlement intentions: Evidence from China," Growth and Change, Wiley Blackwell, vol. 51(3), pages 1239-1258, September.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0204286. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.