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Proof-of-concept study of an at-home, engaging, digital intervention for pediatric ADHD

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  • Naomi O Davis
  • Jeffrey Bower
  • Scott H Kollins

Abstract

Objective: Pharmacological and behavioral therapies have limited impact on the distinct neurocognitive impairments associated with ADHD, and existing cognitive training programs have shown limited efficacy. This proof-of-concept study assessed treatment acceptability and explored outcomes for a novel digital treatment targeting cognitive processes implicated in ADHD. Method: Participants included 40 children with ADHD and 40 children without ADHD. Following psychiatric screening, ADHD ratings, and baseline neuropsychological measures, participants completed 28-days of at-home treatment. Neuropsychological assessment was repeated at end-of-study along with treatment satisfaction measures. Results: Eighty-four percent of treatment sessions were completed and ratings showed strong intervention appeal. Significant improvements were observed on a computerized attention task for the ADHD group and a highly impaired ADHD High Severity subgroup. There was no change for the non-ADHD group. Spatial working memory also improved for the ADHD group and the ADHD High Severity subgroup. Conclusion: Findings provide preliminary support that this treatment may improve attention, working memory, and inhibition in children with ADHD. Future research requires larger-scale randomized controlled trials that also evaluate treatment impact on functional impairments. Trial registration: ClinicalTrials.gov NCT01943539

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  • Naomi O Davis & Jeffrey Bower & Scott H Kollins, 2018. "Proof-of-concept study of an at-home, engaging, digital intervention for pediatric ADHD," PLOS ONE, Public Library of Science, vol. 13(1), pages 1-19, January.
    • Handle: RePEc:plo:pone00:0189749
    DOI: 10.1371/journal.pone.0189749
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    References listed on IDEAS

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    1. Nicole Schatz & Gregory Fabiano & Charles Cunningham & Susan dosReis & Daniel Waschbusch & Stephanie Jerome & Kellina Lupas & Karen Morris, 2015. "Systematic Review of Patients’ and Parents’ Preferences for ADHD Treatment Options and Processes of Care," The Patient: Patient-Centered Outcomes Research, Springer;International Academy of Health Preference Research, vol. 8(6), pages 483-497, December.
    2. Patrick de Zeeuw & Juliette Weusten & Sarai van Dijk & Janna van Belle & Sarah Durston, 2012. "Deficits in Cognitive Control, Timing and Reward Sensitivity Appear to be Dissociable in ADHD," PLOS ONE, Public Library of Science, vol. 7(12), pages 1-9, December.
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