IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0156051.html
   My bibliography  Save this article

Increased Mortality in Metal-on-Metal versus Non-Metal-on-Metal Primary Total Hip Arthroplasty at 10 Years and Longer Follow-Up: A Systematic Review and Meta-Analysis

Author

Listed:
  • B G Pijls
  • J M T A Meessen
  • J W Schoones
  • M Fiocco
  • H J L van der Heide
  • A Sedrakyan
  • R G H H Nelissen

Abstract

Importance: There are concerns about increased mortality in patients with metal-on-metal bearings in total hip arthroplasty (THA). Objective: To determine the mortality and the morbidity in patients with metal-on-metal articulations (MOM THA) compared to patients with non-metal-on-metal articulations (non-MOM THA) after primary total hip arthroplasty. Data Sources: Search of PubMed, MEDLINE, EMBASE, Web of Science, Cochrane, CINAHL, AcademicSearchPremier, ScienceDirect, Wiley and clinical trial registers through March 2015, augmented by a hand search of references from the included articles. No language restrictions were applied. Study Selection: Two reviewers screened and identified randomised controlled trials and observational studies of primary total hip arthroplasty comparing MOM THA with non-MOM THA. Data Extraction and Synthesis: Two reviewers independently extracted study data and assessed risk of bias. Risk differences (RD) were calculated with random effect models. Meta-regression was used to explore modifying factors. Main Outcomes and Measures: Difference in mortality and difference in morbidity expressed as revisions and medical complications between patients with MOM THA and non-MOM THA. Results: Forty-seven studies were included, comprising 4,000 THA in randomised trials and over 500,000 THA in observational studies. For mortality, random effects analysis revealed a higher pooled RD of 0.7%, 95%, confidence interval (CI) [0.0%, 2.3%], I-square 42%; the heterogeneity was explained by differences in follow-up. When restricted to studies with long term follow-up (i.e. 10 years or more), the RD for mortality was 8.5%, 95%, CI [5.8%, 11.2%]; number needed to treat was 12. Further subgroup analyses and meta-regression random effects models revealed no evidence for other moderator variables (study level covariates, e.g. resurfacing vs. non-resurfacing MOM) than follow-up duration. The quality of the evidence presented in this meta-analysis was characterized as moderate according to the CLEAR-NPT (for non-pharmacological trials) and Cochrane risk of bias Table. Conclusions and Relevance: Meta-analysis suggests there may be an increased long-term risk of mortality and revision surgery for patients with MOM THA compared to patients with non-MOM THA. Registration: PROSPERO 2014:CRD42014007417

Suggested Citation

  • B G Pijls & J M T A Meessen & J W Schoones & M Fiocco & H J L van der Heide & A Sedrakyan & R G H H Nelissen, 2016. "Increased Mortality in Metal-on-Metal versus Non-Metal-on-Metal Primary Total Hip Arthroplasty at 10 Years and Longer Follow-Up: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(6), pages 1-17, June.
  • Handle: RePEc:plo:pone00:0156051
    DOI: 10.1371/journal.pone.0156051
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156051
    Download Restriction: no

    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0156051&type=printable
    Download Restriction: no

    File URL: https://libkey.io/10.1371/journal.pone.0156051?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    2. Viechtbauer, Wolfgang, 2010. "Conducting Meta-Analyses in R with the metafor Package," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 36(i03).
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Piers Steel & Sjoerd Beugelsdijk & Herman Aguinis, 2021. "The anatomy of an award-winning meta-analysis: Recommendations for authors, reviewers, and readers of meta-analytic reviews," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 52(1), pages 23-44, February.
    2. Kelly R Moran & Sara Y Del Valle, 2016. "A Meta-Analysis of the Association between Gender and Protective Behaviors in Response to Respiratory Epidemics and Pandemics," PLOS ONE, Public Library of Science, vol. 11(10), pages 1-25, October.
    3. Evangelos Danopoulos & Maureen Twiddy & Jeanette M Rotchell, 2020. "Microplastic contamination of drinking water: A systematic review," PLOS ONE, Public Library of Science, vol. 15(7), pages 1-23, July.
    4. Boshra H. Namin & Torvald Øgaard & Jo Røislien, 2021. "Workplace Incivility and Turnover Intention in Organizations: A Meta-Analytic Review," IJERPH, MDPI, vol. 19(1), pages 1-19, December.
    5. Ruohuang Jiao & Wojtek Przepiorka & Vincent Buskens, 2022. "Moderators of reputation effects in peer-to-peer online markets: a meta-analytic model selection approach," Journal of Computational Social Science, Springer, vol. 5(1), pages 1041-1067, May.
    6. Pedro Silva Moreira & Pedro R Almeida & Hugo Leite-Almeida & Nuno Sousa & Patrício Costa, 2016. "Impact of Chronic Stress Protocols in Learning and Memory in Rodents: Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(9), pages 1-24, September.
    7. repec:cup:judgdm:v:17:y:2022:i:4:p:720-744 is not listed on IDEAS
    8. Mohith M. Varma & Shengzi Zeng & Laura Singh & Emily A. Holmes & Jingyun Huang & Man Hey Chiu & Xiaoqing Hu, 2024. "A systematic review and meta-analysis of experimental methods for modulating intrusive memories following lab-analogue trauma exposure in non-clinical populations," Nature Human Behaviour, Nature, vol. 8(10), pages 1968-1987, October.
    9. Woodley of Menie, Michael A. & Peñaherrera-Aguirre, Mateo & Sarraf, Matthew A., 2022. "Signs of a Flynn effect in rodents? Secular differentiation of the manifold of general cognitive ability in laboratory mice (Mus musculus) and Norwegian rats (Rattus norvegicus) over a century—Results," Intelligence, Elsevier, vol. 95(C).
    10. Chad K Bush & Dayaamayi Kurimella & Lee J S Cross & Katherine R Conner & Sheryl Martin-Schild & Jiang He & Changwei Li & Jing Chen & Tanika Kelly, 2016. "Endovascular Treatment with Stent-Retriever Devices for Acute Ischemic Stroke: A Meta-Analysis of Randomized Controlled Trials," PLOS ONE, Public Library of Science, vol. 11(1), pages 1-19, January.
    11. Laurens Manning & Moses Laman & Wendy A Davis & Timothy M E Davis, 2014. "Clinical Features and Outcome in Children with Severe Plasmodium falciparum Malaria: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 9(2), pages 1-11, February.
    12. Mikkel Wallentin, 2018. "Sex differences in post-stroke aphasia rates are caused by age. A meta-analysis and database query," PLOS ONE, Public Library of Science, vol. 13(12), pages 1-18, December.
    13. Ewa Zasadzka & Anna Pieczyńska & Tomasz Trzmiel & Paweł Kleka & Mariola Pawlaczyk, 2021. "Correlation between Handgrip Strength and Depression in Older Adults—A Systematic Review and a Meta-Analysis," IJERPH, MDPI, vol. 18(9), pages 1-15, April.
    14. Dominika Wilczyńska & Wen Qi & José Carlos Jaenes & David Alarcón & María José Arenilla & Mariusz Lipowski, 2022. "Burnout and Mental Interventions among Youth Athletes: A Systematic Review and Meta-Analysis of the Studies," IJERPH, MDPI, vol. 19(17), pages 1-17, August.
    15. van Aert, Robbie Cornelis Maria & van Assen, Marcel A. L. M., 2018. "P-uniform," MetaArXiv zqjr9, Center for Open Science.
    16. Briana N. M. Hagen & Charlotte B. Winder & Jared Wootten & Carrie K. McMullen & Andria Jones-Bitton, 2020. "A Systematic Review and Meta-Analysis of Depression among Farming Populations Worldwide," IJERPH, MDPI, vol. 17(24), pages 1-15, December.
    17. Sergio Nolazco & Kaspar Delhey & Shinichi Nakagawa & Anne Peters, 2022. "Ornaments are equally informative in male and female birds," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    18. Schubert, Anna-Lena, 2019. "A meta-analysis of the worst performance rule," Intelligence, Elsevier, vol. 73(C), pages 88-100.
    19. Boris Forthmann & Karin Kaczykowski & Mathias Benedek & Heinz Holling, 2023. "The Manic Idea Creator? A Review and Meta-Analysis of the Relationship between Bipolar Disorder and Creative Cognitive Potential," IJERPH, MDPI, vol. 20(13), pages 1-39, June.
    20. Fernando Santini & Wagner Junior Ladeira & Diego Costa Pinto & Márcia Maurer Herter & Claudio Hoffmann Sampaio & Barry J. Babin, 2020. "Customer engagement in social media: a framework and meta-analysis," Journal of the Academy of Marketing Science, Springer, vol. 48(6), pages 1211-1228, November.
    21. Merga Bayssa & Sintayehu Yigrem & Simret Betsha & Adugna Tolera, 2021. "Production, reproduction and some adaptation characteristics of Boran cattle breed under changing climate: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 16(5), pages 1-26, May.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0156051. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.