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Hypoglycemia and Medical Expenses in Patients with Type 2 Diabetes Mellitus: An Analysis Based on the Korea National Diabetes Program Cohort

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Listed:
  • Sang Youl Rhee
  • Soo Min Hong
  • Suk Chon
  • Kyu Jeung Ahn
  • Sung Hoon Kim
  • Sei Hyun Baik
  • Yong Soo Park
  • Moon Suk Nam
  • Kwan Woo Lee
  • Jeong-Taek Woo
  • Young Seol Kim

Abstract

Background and Aims: Hypoglycemia is one of the most important adverse events in individuals with type 2 diabetes mellitus (T2DM). However, hypoglycemia-related events are usually overlooked and have been documented less in clinical practice. Materials and Methods: We evaluated the incidence, clinical characteristics, and medical expenses of hypoglycemia related events in T2DM patients based on the Korea National Diabetes Program (KNDP), which is the largest multi-center, prospective cohort in Korea (n = 4,350). For accurate outcomes, the KNDP data were merged with claims data from the Health Insurance Review and Assessment Service (HIRA) of Korea. Results: During a median follow-up period of 3.23 years (95% CI: 3.14, 3.19), 88 subjects (2.02%) were newly diagnosed with hypoglycemia, and the incidence of hypoglycemia was 6.44 cases per 1,000 person-years (PY). Individuals with hypoglycemia were significantly older (59.7±10.7 vs. 53.3±10.4 years, p

Suggested Citation

  • Sang Youl Rhee & Soo Min Hong & Suk Chon & Kyu Jeung Ahn & Sung Hoon Kim & Sei Hyun Baik & Yong Soo Park & Moon Suk Nam & Kwan Woo Lee & Jeong-Taek Woo & Young Seol Kim, 2016. "Hypoglycemia and Medical Expenses in Patients with Type 2 Diabetes Mellitus: An Analysis Based on the Korea National Diabetes Program Cohort," PLOS ONE, Public Library of Science, vol. 11(2), pages 1-10, February.
    • Handle: RePEc:plo:pone00:0148630
    DOI: 10.1371/journal.pone.0148630
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    References listed on IDEAS

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    1. Joanna Leśniowska & Agata Schubert & Michał Wojna & Iwona Skrzekowska-Baran & Marta Fedyna, 2014. "Costs of diabetes and its complications in Poland," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 15(6), pages 653-660, July.
    2. Jonas Lundkvist & Christian Berne & Björn Bolinder & Linus Jönsson, 2005. "The economic and quality of life impact of hypoglycemia," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 6(3), pages 197-202, September.
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