IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0136855.html
   My bibliography  Save this article

Patient-Provider Interactions Affect Symptoms in Gastroesophageal Reflux Disease: A Pilot Randomized, Double-Blind, Placebo-Controlled Trial

Author

Listed:
  • Michelle L Dossett
  • Lin Mu
  • Roger B Davis
  • Iris R Bell
  • Anthony J Lembo
  • Ted J Kaptchuk
  • Gloria Y Yeh

Abstract

Background: It is unclear whether the benefits that some patients derive from complementary and integrative medicine (CIM) are related to the therapies recommended or to the consultation process as some CIM provider visits are more involved than conventional medical visits. Many patients with gastrointestinal conditions seek out CIM therapies, and prior work has demonstrated that the quality of the patient-provider interaction can improve health outcomes in irritable bowel syndrome, however, the impact of this interaction on gastroesophageal reflux disease (GERD) is unknown. We aimed to assess the safety and feasibility of conducting a 2x2 factorial design study preliminarily exploring the impact of the patient-provider interaction, and the effect of an over-the-counter homeopathic product, Acidil, on symptoms and health-related quality of life in subjects with GERD. Methods: 24 subjects with GERD-related symptoms were randomized in a 2x2 factorial design to receive 1) either a standard visit based on an empathic conventional primary care evaluation or an expanded visit with questions modeled after a CIM consultation and 2) either Acidil or placebo for two weeks. Subjects completed a daily GERD symptom diary and additional measures of symptom severity and health-related quality of life. Results: There was no significant difference in GERD symptom severity between the Acidil and placebo groups from baseline to follow-up (p = 0.41), however, subjects who received the expanded visit were significantly more likely to report a 50% or greater improvement in symptom severity compared to subjects who received the standard visit (p = 0.01). Total consultation length, perceived empathy, and baseline beliefs in CIM were not associated with treatment outcomes. Conclusion: An expanded patient-provider visit resulted in greater GERD symptom improvement than a standard empathic medical visit. CIM consultations may have enhanced placebo effects, and further studies to assess the active components of this visit-based intervention are warranted. Trial Registration: ClinicalTrials.gov NCT01915173

Suggested Citation

  • Michelle L Dossett & Lin Mu & Roger B Davis & Iris R Bell & Anthony J Lembo & Ted J Kaptchuk & Gloria Y Yeh, 2015. "Patient-Provider Interactions Affect Symptoms in Gastroesophageal Reflux Disease: A Pilot Randomized, Double-Blind, Placebo-Controlled Trial," PLOS ONE, Public Library of Science, vol. 10(9), pages 1-13, September.
    • Handle: RePEc:plo:pone00:0136855
    DOI: 10.1371/journal.pone.0136855
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136855
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0136855&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0136855?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. John M Kelley & Gordon Kraft-Todd & Lidia Schapira & Joe Kossowsky & Helen Riess, 2014. "The Influence of the Patient-Clinician Relationship on Healthcare Outcomes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials," PLOS ONE, Public Library of Science, vol. 9(4), pages 1-7, April.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Karen R. Sepucha & Steven J. Atlas & Yuchiao Chang & Andrew Freiberg & Henrik Malchau & Mahima Mangla & Harry Rubash & Leigh H. Simmons & Thomas Cha, 2018. "Informed, Patient-Centered Decisions Associated with Better Health Outcomes in Orthopedics: Prospective Cohort Study," Medical Decision Making, , vol. 38(8), pages 1018-1026, November.
    2. Laura Tam & Gail Garvey & Judith Meiklejohn & Jennifer Martin & Jon Adams & Euan Walpole & Michael Fay & Patricia Valery, 2018. "Exploring Positive Survivorship Experiences of Indigenous Australian Cancer Patients," IJERPH, MDPI, vol. 15(1), pages 1-12, January.
    3. Quan-Hoang Vuong & Tung-Manh Ho & Hong-Kong Nguyen & Thu-Trang Vuong, 2018. "Healthcare consumers’ sensitivity to costs: a reflection on behavioural economics from an emerging market," Palgrave Communications, Palgrave Macmillan, vol. 4(1), pages 1-10, December.
    4. Ying Lau & Kin Sun Chan, 2018. "Psychometric evaluation of the Chinese version of the fear of intimacy with helping professionals scale," PLOS ONE, Public Library of Science, vol. 13(5), pages 1-18, May.
    5. Ana Maria Rodriguez & Beth A Lown, 2019. "Measuring compassionate healthcare with the 12-item Schwartz Center Compassionate Care Scale," PLOS ONE, Public Library of Science, vol. 14(9), pages 1-16, September.
    6. Hardman, Doug & Geraghty, Adam W.A. & Lown, Mark & Bishop, Felicity L., 2020. "Subjunctive medicine: Enacting efficacy in general practice," Social Science & Medicine, Elsevier, vol. 245(C).
    7. Óscar Rodríguez-Nogueira & Jaume Morera Balaguer & Abel Nogueira López & Juan Roldán Merino & José-Martín Botella-Rico & Sonia Del Río-Medina & Antonio R Moreno Poyato, 2020. "The psychometric properties of the person-centered therapeutic relationship in physiotherapy scale," PLOS ONE, Public Library of Science, vol. 15(11), pages 1-16, November.
    8. Francesco Tramonti & Franco Giorgi & Annibale Fanali, 2021. "Systems thinking and the biopsychosocial approach: A multilevel framework for patient‐centred care," Systems Research and Behavioral Science, Wiley Blackwell, vol. 38(2), pages 215-230, March.
    9. Luther, Louisa & Benkenstein, Martin & Rummelhagen, Katja, 2016. "Enhancing patients' hospital satisfaction by taking advantage of interpersonal similarity," Journal of Retailing and Consumer Services, Elsevier, vol. 30(C), pages 50-58.
    10. Kovacs, Roxanne J. & Lagarde, Mylene & Cairns, John, 2022. "Can patients improve the quality of care they receive? Experimental evidence from Senegal," World Development, Elsevier, vol. 150(C).
    11. Meredith A. Perry & Bernadette Jones & Matthew Jenkins & Hemakumar Devan & Alister Neill & Tristram Ingham, 2023. "Health System Factors Affecting the Experience of Non-Invasive Ventilation Provision of People with Neuromuscular Disorders in New Zealand," IJERPH, MDPI, vol. 20(6), pages 1-19, March.
    12. Krunoslav Nikodem & Marko Ćurković & Ana Borovečki, 2022. "Trust in the Healthcare System and Physicians in Croatia: A Survey of the General Population," IJERPH, MDPI, vol. 19(2), pages 1-18, January.
    13. Lazzaro-Salazar, Mariana & Pujol-Cols, Lucas J., 2022. "Instrumentos estandarizados para medir la relación médico-paciente: una revisión sistemática de la literatura internacional e iberoamericana," Nülan. Deposited Documents 3753, Universidad Nacional de Mar del Plata, Facultad de Ciencias Económicas y Sociales, Centro de Documentación.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0136855. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.