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Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial

Author

Listed:
  • Els Meeuwsen
  • René Melis
  • Geert van der Aa
  • Gertie Golüke-Willemse
  • Benoit de Leest
  • Frank van Raak
  • Carla Schölzel-Dorenbos
  • Desiree Verheijen
  • Frans Verhey
  • Marieke Visser
  • Claire Wolfs
  • Eddy Adang
  • Marcel Olde Rikkert

Abstract

Objective: To evaluate the cost-effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared to general practitioners’ care. Methods: A multicentre randomised trial with 175 community dwelling patients newly diagnosed with mild to moderate dementia, and their informal caregivers, with twelve months’ follow-up. Cost-effectiveness was evaluated from a societal point of view and presented as incremental cost per quality adjusted life year. To establish cost-effectiveness, a cost-utility analysis was conducted using utilities based on the EQ-5D. Uncertainty surrounding the incremental cost-effectiveness ratio (difference in costs divided by difference in effects) was calculated by bootstrapping from the original data. Results: Compared to general practitioners’ care, treatment by the memory clinics was on average €1024 (95% CI: −€7723 to €5674) cheaper, and showed a non-significant decrease of 0.025 (95% CI: −0.114 to 0.064) quality adjusted life years. The incremental cost-effectiveness point estimate from the bootstrap simulation was € 41 442 per QALY lost if one would use memory clinic care instead of general practitioner care. Conclusion: No evidence was found that memory clinics were more cost-effective compared to general practitioners with regard to post-diagnosis treatment and coordination of care of patients with dementia in the first year after diagnosis. Trial Registration: ClinicalTrials.gov NCT00554047

Suggested Citation

  • Els Meeuwsen & René Melis & Geert van der Aa & Gertie Golüke-Willemse & Benoit de Leest & Frank van Raak & Carla Schölzel-Dorenbos & Desiree Verheijen & Frans Verhey & Marieke Visser & Claire Wolfs & , 2013. "Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial," PLOS ONE, Public Library of Science, vol. 8(11), pages 1-7, November.
  • Handle: RePEc:plo:pone00:0079797
    DOI: 10.1371/journal.pone.0079797
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    References listed on IDEAS

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    1. Drummond, Michael F. & Sculpher, Mark J. & Torrance, George W. & O'Brien, Bernie J. & Stoddart, Greg L., 2005. "Methods for the Economic Evaluation of Health Care Programmes," OUP Catalogue, Oxford University Press, edition 3, number 9780198529453.
    2. Linus Jönsson & Anders Wimo, 2009. "The Cost of Dementia in Europe," PharmacoEconomics, Springer, vol. 27(5), pages 391-403, May.
    3. Ben A. Van Hout & Maiwenn J. Al & Gilad S. Gordon & Frans F. H. Rutten, 1994. "Costs, effects and C/E‐ratios alongside a clinical trial," Health Economics, John Wiley & Sons, Ltd., vol. 3(5), pages 309-319, September.
    4. L. M. Lamers & J. McDonnell & P. F. M. Stalmeier & P. F. M. Krabbe & J. J. V. Busschbach, 2006. "The Dutch tariff: results and arguments for an effective design for national EQ‐5D valuation studies," Health Economics, John Wiley & Sons, Ltd., vol. 15(10), pages 1121-1132, October.
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