IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0078509.html
   My bibliography  Save this article

Control Efficacy of Annual Community-Wide Treatment against Schistosoma japonicum in China: A Meta-Analysis

Author

Listed:
  • Jing Su
  • Da-Bing Lu
  • Xia Zhou
  • Su-Rong Wang
  • Hong-Xiang Zhuge

Abstract

Backgrounds: Human schistosomiasis is caused by schistosome, with annual loss of over 70 million disability adjusted life years in the world. China is endemic with Schistosoma japonicum and large-scale chemotherapy with praziquantel has become the mainstay of control in China since 1990s. However, the control effects of mass treatment in the field have been uneven. Moreover, mass treatment has come into a wide use in other countries with limited health resources. Therefore, a better understanding of the control effect of mass treatment is in an urgent need. Methods: We performed a systematic search of the literature to investigate the control efficiency of annual community-wide treatment (ACWT, treatment to an entire community without any preliminary screening) with a single dose of PZQ (40 mg kg−1 bodyweight) against schistosome in humans in China. Three Chinese literature databases, including China National Knowledge Infrastructure, WanFang and Chinese Scientific Journal Databases, and the PubMed were searched. Pooled prevalence ratios (prevalence after to before treatment) were used to assess effect. Our protocol is available on PROSPERO (No. CRD42013003628). Results: 22 articles were included. Meta-analyses on data from 18 studies on one round of ACWT, 17 studies on two consecutive rounds and 6 studies on three consecutive rounds were performed. The results showed control effects of ACWT plus other measures were statistically significant, with prevalence ratios being 0.38 (0.31, 0.46) for one round, 0.28 (0.22, 0.35) for two rounds and 0.22 (0.10, 0.46) for three rounds. When ACWT was performed alone or with health education only, the values for one and two rounds were 0.389 (0.307, 0.492) and 0.348 (0.300, 0.403), respectively. Conclusions: The control effect of ACWT alone or with other measures is significant and increases with the number of rounds. Such program is recommended in high endemic areas and the criteria yet merit further assessment.

Suggested Citation

  • Jing Su & Da-Bing Lu & Xia Zhou & Su-Rong Wang & Hong-Xiang Zhuge, 2013. "Control Efficacy of Annual Community-Wide Treatment against Schistosoma japonicum in China: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 8(11), pages 1-9, November.
    • Handle: RePEc:plo:pone00:0078509
    DOI: 10.1371/journal.pone.0078509
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078509
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0078509&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0078509?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Tie-Wu Jia & Sara Melville & Jürg Utzinger & Charles H King & Xiao-Nong Zhou, 2012. "Soil-Transmitted Helminth Reinfection after Drug Treatment: A Systematic Review and Meta-Analysis," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 6(5), pages 1-11, May.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Aisha Ummi Jibrin Isah & Obinna Ikechukwu Ekwunife & Izuchukwu Loveth Ejie & Olena Mandrik, 2020. "Effects of nutritional supplements on the re-infection rate of soil-transmitted helminths in school-age children: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 15(8), pages 1-20, August.
    2. Mikhael D. Manurung & Friederike Sonnet & Marie-Astrid Hoogerwerf & Jacqueline J. Janse & Yvonne Kruize & Laura de Bes-Roeleveld & Marion König & Alex Loukas & Benjamin G. Dewals & Taniawati Supali & , 2024. "Controlled human hookworm infection remodels plasmacytoid dendritic cells and regulatory T cells towards profiles seen in natural infections in endemic areas," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    3. Birgit Nikolay & Charles S Mwandawiro & Jimmy H Kihara & Collins Okoyo & Jorge Cano & Mariam T Mwanje & Hadley Sultani & Dorcas Alusala & Hugo C Turner & Caroline Teti & Josh Garn & Matthew C Freeman , 2015. "Understanding Heterogeneity in the Impact of National Neglected Tropical Disease Control Programmes: Evidence from School-Based Deworming in Kenya," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 9(9), pages 1-20, September.
    4. Amy J. Pickering & Sammy M. Njenga & Lauren Steinbaum & Jenna Swarthout & Audrie Lin & Benjamin F. Arnold & Christine P. Stewart & Holly N. Dentz & MaryAnne Mureithi & Benard Chieng & Marlene Wolfe & , "undated". "Effects of Single and Integrated Water, Sanitation, Handwashing, and Nutrition Interventions on Child Soil-Transmitted Helminth and Giardia Infections: A Cluster-Randomized Controlled Trial in Rural K," Mathematica Policy Research Reports b056c901c24c4dad92672a0eb, Mathematica Policy Research.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0078509. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.