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Systematic Review of Economic Evaluations of Preparedness Strategies and Interventions against Influenza Pandemics

Author

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  • Román Pérez Velasco
  • Naiyana Praditsitthikorn
  • Kamonthip Wichmann
  • Adun Mohara
  • Surachai Kotirum
  • Sripen Tantivess
  • Constanza Vallenas
  • Hande Harmanci
  • Yot Teerawattananon

Abstract

Background: Although public health guidelines have implications for resource allocation, these issues were not explicitly considered in previous WHO pandemic preparedness and response guidance. In order to ensure a thorough and informed revision of this guidance following the H1N1 2009 pandemic, a systematic review of published and unpublished economic evaluations of preparedness strategies and interventions against influenza pandemics was conducted. Methods: The search was performed in September 2011 using 10 electronic databases, 2 internet search engines, reference list screening, cited reference searching, and direct communication with relevant authors. Full and partial economic evaluations considering both costs and outcomes were included. Conversely, reviews, editorials, and studies on economic impact or complications were excluded. Studies were selected by 2 independent reviewers. Results: 44 studies were included. Although most complied with the cost effectiveness guidelines, the quality of evidence was limited. However, the data sources used were of higher quality in economic evaluations conducted after the 2009 H1N1 pandemic. Vaccination and drug regimens were varied. Pharmaceutical plus non-pharmaceutical interventions are relatively cost effective in comparison to vaccines and/or antivirals alone. Pharmaceutical interventions vary from cost saving to high cost effectiveness ratios. According to ceiling thresholds (Gross National Income per capita), the reduction of non-essential contacts and the use of pharmaceutical prophylaxis plus the closure of schools are amongst the cost effective strategies for all countries. However, quarantine for household contacts is not cost effective even for low and middle income countries. Conclusion: The available evidence is generally inconclusive regarding the cost effectiveness of preparedness strategies and interventions against influenza pandemics. Studies on their effectiveness and cost effectiveness should be readily implemented in forthcoming events that also involve the developing world. Guidelines for assessing the impact of disease and interventions should be drawn up to facilitate these studies.

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  • Román Pérez Velasco & Naiyana Praditsitthikorn & Kamonthip Wichmann & Adun Mohara & Surachai Kotirum & Sripen Tantivess & Constanza Vallenas & Hande Harmanci & Yot Teerawattananon, 2012. "Systematic Review of Economic Evaluations of Preparedness Strategies and Interventions against Influenza Pandemics," PLOS ONE, Public Library of Science, vol. 7(2), pages 1-9, February.
    • Handle: RePEc:plo:pone00:0030333
    DOI: 10.1371/journal.pone.0030333
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    References listed on IDEAS

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    1. Anna K. Lugnér & Sido D. Mylius & Jacco Wallinga, 2010. "Dynamic versus static models in cost‐effectiveness analyses of anti‐viral drug therapy to mitigate an influenza pandemic," Health Economics, John Wiley & Sons, Ltd., vol. 19(5), pages 518-531, May.
    2. Bruce Y Lee & Sarah M McGlone & Rachel R Bailey & Ann E Wiringa & Shanta M Zimmer & Kenneth J Smith & Richard K Zimmerman, 2010. "To Test or to Treat? An Analysis of Influenza Testing and Antiviral Treatment Strategies Using Economic Computer Modeling," PLOS ONE, Public Library of Science, vol. 5(6), pages 1-11, June.
    3. Vernon J Lee & Mei Yin Tok & Vincent T Chow & Kai Hong Phua & Eng Eong Ooi & Paul A Tambyah & Mark I Chen, 2009. "Economic Analysis of Pandemic Influenza Vaccination Strategies in Singapore," PLOS ONE, Public Library of Science, vol. 4(9), pages 1-8, September.
    4. Lars Jonung & Werner Roeger, 2006. "The macroeconomic effects of a pandemic in Europe - A model-based assessment," European Economy - Economic Papers 2008 - 2015 251, Directorate General Economic and Financial Affairs (DG ECFIN), European Commission.
    5. Lisa A Prosser & Tara A Lavelle & Anthony E Fiore & Carolyn B Bridges & Carrie Reed & Seema Jain & Kelly M Dunham & Martin I Meltzer, 2011. "Cost-Effectiveness of 2009 Pandemic Influenza A(H1N1) Vaccination in the United States," PLOS ONE, Public Library of Science, vol. 6(7), pages 1-11, July.
    6. Yot Teerawattananon & Steve Russell & Miranda Mugford, 2007. "A Systematic Review of Economic Evaluation Literature in Thailand," PharmacoEconomics, Springer, vol. 25(6), pages 467-479, June.
    7. Dutta, Arin, 2008. "The effectiveness of policies to control a human influenza pandemic : a literature review," Policy Research Working Paper Series 4524, The World Bank.
    8. S. Deuffic-Burban & X. Lenne & B. Dervaux & J. Poissy & X. Lemaire & C. Sloan & F. Carrat & J.C. Desenclos & J.F. Delfraissis & Y. Yazdanpanah, 2009. "Targeted vs. systematic early antiviral treatment against A(H1N1)v influenza with neuraminidase inhibitors in patients with influenza-like symptoms: Clinical and economic impact," Post-Print hal-00436419, HAL.
    9. Nilimesh Halder & Joel K Kelso & George J Milne, 2011. "Cost-Effective Strategies for Mitigating a Future Influenza Pandemic with H1N1 2009 Characteristics," PLOS ONE, Public Library of Science, vol. 6(7), pages 1-11, July.
    10. Carrasco, L R & Lee, V J & Chen, M I & Matchar, D B & Thompson, J P & Cook, A R, 2011. "Strategies for antiviral stockpiling for future influenza pandemics: a global epidemic-economic perspective," MPRA Paper 57763, University Library of Munich, Germany.
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    Cited by:

    1. Xinhai Li & Wenjun Geng & Huidong Tian & Dejian Lai, 2013. "Was Mandatory Quarantine Necessary in China for Controlling the 2009 H1N1 Pandemic?," IJERPH, MDPI, vol. 10(10), pages 1-11, September.
    2. Itamar Megiddo & Dusan Drabik & Tim Bedford & Alec Morton & Justus Wesseler & Ramanan Laxminarayan, 2019. "Investing in antibiotics to alleviate future catastrophic outcomes: What is the value of having an effective antibiotic to mitigate pandemic influenza?," Health Economics, John Wiley & Sons, Ltd., vol. 28(4), pages 556-571, April.
    3. Peter A.G. van Bergeijk, 2021. "Pandemic Economics," Books, Edward Elgar Publishing, number 20401.
    4. Caroline Orset, 2017. "People's preferences for epidemic prevention measures," Working Papers 2017/01, INRA, Economie Publique.
    5. Caroline Orset, 2018. "People’s perception and cost-effectiveness of home confinement during an influenza pandemic: evidence from the French case," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 19(9), pages 1335-1350, December.
    6. Caroline Orset, 2017. "Effectiveness of confinement to home during an influenza pandemic: evidence from the French case," Working Papers hal-01500902, HAL.
    7. Klas Kellerborg & Werner Brouwer & Pieter Baal, 2020. "Costs and benefits of interventions aimed at major infectious disease threats: lessons from the literature," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 21(9), pages 1329-1350, December.
    8. Patrick Saunders-Hastings & Jane Reisman & Daniel Krewski, 2016. "Assessing the State of Knowledge Regarding the Effectiveness of Interventions to Contain Pandemic Influenza Transmission: A Systematic Review and Narrative Synthesis," PLOS ONE, Public Library of Science, vol. 11(12), pages 1-17, December.

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