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Effect of a Community-Based Nursing Intervention on Mortality in Chronically Ill Older Adults: A Randomized Controlled Trial

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  • Kenneth D Coburn
  • Sherry Marcantonio
  • Robert Lazansky
  • Maryellen Keller
  • Nancy Davis

Abstract

Kenneth Coburn and colleagues report findings from a randomized trial evaluating the effects of a complex nursing intervention on mortality risk among older individuals diagnosed with chronic health conditions. Background: Improving the health of chronically ill older adults is a major challenge facing modern health care systems. A community-based nursing intervention developed by Health Quality Partners (HQP) was one of 15 different models of care coordination tested in randomized controlled trials within the Medicare Coordinated Care Demonstration (MCCD), a national US study. Evaluation of the HQP program began in 2002. The study reported here was designed to evaluate the survival impact of the HQP program versus usual care up to five years post-enrollment. Methods and Findings: HQP enrolled 1,736 adults aged 65 and over, with one or more eligible chronic conditions (coronary artery disease, heart failure, diabetes, asthma, hypertension, or hyperlipidemia) during the first six years of the study. The intervention group (n = 873) was offered a comprehensive, integrated, and tightly managed system of care coordination, disease management, and preventive services provided by community-based nurse care managers working collaboratively with primary care providers. The control group (n = 863) received usual care. Overall, a 25% lower relative risk of death (hazard ratio [HR] 0.75 [95% CI 0.57–1.00], p = 0.047) was observed among intervention participants with 86 (9.9%) deaths in the intervention group and 111 (12.9%) deaths in the control group during a mean follow-up of 4.2 years. When covariates for sex, age group, primary diagnosis, perceived health, number of medications taken, hospital stays in the past 6 months, and tobacco use were included, the adjusted HR was 0.73 (95% CI 0.55–0.98, p = 0.033). Subgroup analyses did not demonstrate statistically significant interaction effects for any subgroup. No suspected program-related adverse events were identified. Conclusions: The HQP model of community-based nurse care management appeared to reduce all-cause mortality in chronically ill older adults. Limitations of the study are that few low-income and non-white individuals were enrolled and implementation was in a single geographic region of the US. Additional research to confirm these findings and determine the model's scalability and generalizability is warranted. Trial Registration: ClinicalTrials.gov NCT01071967 : Please see later in the article for the Editors' Summary Background: In almost every country in the world, the proportion of people aged over 60 years is growing faster than any other age group because of increased life expectancy. This demographic change has several implications for public health, especially as older age is a risk factor for many chronic diseases—diseases of long duration and generally slow progression. Chronic diseases, such as heart disease, stroke, cancer, chronic respiratory diseases, and diabetes, are by far the leading cause of death in the world, representing almost two-thirds of all deaths. Therefore in most countries, the challenge of managing increasingly ageing populations who have chronic illnesses demands an urgent response and countries such as the United States are actively researching possible solutions. Why Was This Study Done?: Some studies suggest that innovations in chronic disease management that are led by nurses may help address the epidemic of chronic diseases by increasing the quality and reducing the cost of care. However, to date, reports of the evaluation of such interventions lack rigor and do not provide evidence of improved long-term health outcomes or reduced health care costs. So in this study, the researchers used the gold standard of research, a randomized controlled trial, to examine the impact of a community-based nurse care management model for older adults with chronic illnesses in the United States as part of a series of studies supported by the Centers for Medicare and Medicaid Services. What Did the Researchers Do and Find?: The researchers recruited eligible patients aged 65 years and over with heart failure, coronary heart disease, asthma, diabetes, hypertension, and/or hyperlipidemia who received traditional Medicare—a fee for service insurance scheme in which beneficiaries can choose to receive their care from any Medicare provider—from participating primary care practices in Pennsylvania. The researchers then categorized patients according to their risk on the basis of several factors including the number of chronic diseases each individual had before randomizing patients to receive usual care or the nurse-led intervention. The intervention included an individualized plan comprising education, symptom monitoring, medication, counseling for adherence, help identifying, arranging, and monitoring community health and social service referrals in addition to group interventions such as weight loss maintenance and exercise classes. The researchers checked whether any participating patients had died by using the online Social Security Death Master File. Then the researchers used a statistical model to calculate the risk of death in both groups. What Do These Findings Mean?: These findings suggest that that community-based nurse care management is associated with a reduction in all-cause mortality among older adults with chronic illnesses who are beneficiaries of the fee for service Medicare scheme in the United States. These findings also support the important role of nurses in improving health outcomes in this group of patients and show the feasibility of implementing this program in collaboration with primary care practices. Future research is needed to test the adaptability, scalability, and generalizability of this model of care. Additional Information: Please access these Web sites via the online version of this summary at http://dx.doi.org/10.1371/journal.pmed.1001265.

Suggested Citation

  • Kenneth D Coburn & Sherry Marcantonio & Robert Lazansky & Maryellen Keller & Nancy Davis, 2012. "Effect of a Community-Based Nursing Intervention on Mortality in Chronically Ill Older Adults: A Randomized Controlled Trial," PLOS Medicine, Public Library of Science, vol. 9(7), pages 1-14, July.
  • Handle: RePEc:plo:pmed00:1001265
    DOI: 10.1371/journal.pmed.1001265
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    Cited by:

    1. Arlene S Bierman, 2012. "Averting an Impending Storm: Can We Reengineer Health Systems to Meet the Needs of Aging Populations?," Working Papers id:5089, eSocialSciences.
    2. Justine S. Sefcik & Darina Petrovsky & Megan Streur & Mark Toles & Melissa O’Connor & Connie M. Ulrich & Sherry Marcantonio & Ken Coburn & Mary D. Naylor & Helene Moriarty, 2018. "“In Our Corner†: A Qualitative Descriptive Study of Patient Engagement in a Community-Based Care Coordination Program," Clinical Nursing Research, , vol. 27(3), pages 258-277, March.
    3. Jonathan Stokes & Maria Panagioti & Rahul Alam & Kath Checkland & Sudeh Cheraghi-Sohi & Peter Bower, 2015. "Effectiveness of Case Management for 'At Risk' Patients in Primary Care: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(7), pages 1-42, July.
    4. Zalika Klemenc‐Ketis & Alenka Terbovc & Bostjan Gomiscek & Janko Kersnik, 2015. "Role of nurse practitioners in reducing cardiovascular risk factors: a retrospective cohort study," Journal of Clinical Nursing, John Wiley & Sons, vol. 24(21-22), pages 3077-3083, November.
    5. Huang, Yu-Ying & Cheng, Shou-Hsia, 2019. "A community pharmacist home visit project for high utilizers under a universal health system: A preliminary assessment," Health Policy, Elsevier, vol. 123(4), pages 373-378.

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