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Provenance and risk in transfer of biological materials

Author

Listed:
  • Jane Nielsen
  • Tania Bubela
  • Don R C Chalmers
  • Amber Johns
  • Linda Kahl
  • Joanne Kamens
  • Charles Lawson
  • John Liddicoat
  • Rebekah McWhirter
  • Ann Monotti
  • James Scheibner
  • Tess Whitton
  • Dianne Nicol

Abstract

Whereas biological materials were once transferred freely, there has been a marked shift in the formalisation of exchanges involving these materials, primarily through the use of Material Transfer Agreements (MTAs). This paper considers how risk aversion dominates MTA negotiations and the impact it may have on scientific progress. Risk aversion is often based on unwarranted fears of incurring liability through the use of a material or loss of control or missing out on commercialisation opportunities. Evidence to date has suggested that complexity tends to permeate even straightforward transactions despite extensive efforts to implement simple, standard MTAs. We argue that in most cases, MTAs need do little more than establish provenance, and any attempt to extend MTAs beyond this simple function constitutes stifling behaviour. Drawing on available examples of favourable practice, we point to a number of strategies that may usefully be employed to reduce risk-averse tendencies, including the promotion of simplicity, education of those engaged in the MTA process, and achieving a cultural shift in the way in which technology transfer office (TTO) success is measured in institutions employing MTAs.

Suggested Citation

  • Jane Nielsen & Tania Bubela & Don R C Chalmers & Amber Johns & Linda Kahl & Joanne Kamens & Charles Lawson & John Liddicoat & Rebekah McWhirter & Ann Monotti & James Scheibner & Tess Whitton & Dianne , 2018. "Provenance and risk in transfer of biological materials," PLOS Biology, Public Library of Science, vol. 16(8), pages 1-9, August.
  • Handle: RePEc:plo:pbio00:2006031
    DOI: 10.1371/journal.pbio.2006031
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    References listed on IDEAS

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    1. Walsh, John P. & Cohen, Wesley M. & Cho, Charlene, 2007. "Where excludability matters: Material versus intellectual property in academic biomedical research," Research Policy, Elsevier, vol. 36(8), pages 1184-1203, October.
    2. Thinh Nguyen, 2007. "Science Commons: Material Transfer Agreement Project," Innovations: Technology, Governance, Globalization, MIT Press, vol. 2(3), pages 137-143, July.
    3. Tania Bubela & Jenilee Guebert & Amrita Mishra, 2015. "Use and Misuse of Material Transfer Agreements: Lessons in Proportionality from Research, Repositories, and Litigation," PLOS Biology, Public Library of Science, vol. 13(2), pages 1-12, February.
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