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On the asymptotics of marginal regression splines with longitudinal data

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  • Zhongyi Zhu
  • Wing K. Fung
  • Xuming He

Abstract

There have been studies on how the asymptotic efficiency of a nonparametric function estimator depends on the handling of the within-cluster correlation when nonparametric regression models are used on longitudinal or cluster data. In particular, methods based on smoothing splines and local polynomial kernels exhibit different behaviour. We show that the generalized estimation equations based on weighted least squares regression splines for the nonparametric function have an interesting property: the asymptotic bias of the estimator does not depend on the working correlation matrix, but the asymptotic variance, and therefore the mean squared error, is minimized when the true correlation structure is specified. This property of the asymptotic bias distinguishes regression splines from smoothing splines. Copyright 2008, Oxford University Press.

Suggested Citation

  • Zhongyi Zhu & Wing K. Fung & Xuming He, 2008. "On the asymptotics of marginal regression splines with longitudinal data," Biometrika, Biometrika Trust, vol. 95(4), pages 907-917.
  • Handle: RePEc:oup:biomet:v:95:y:2008:i:4:p:907-917
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    File URL: http://hdl.handle.net/10.1093/biomet/asn041
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    Cited by:

    1. Gao, Yan & Zhang, Xinyu & Wang, Shouyang & Zou, Guohua, 2016. "Model averaging based on leave-subject-out cross-validation," Journal of Econometrics, Elsevier, vol. 192(1), pages 139-151.
    2. Kangning Wang & Lu Lin, 2019. "Robust and efficient estimator for simultaneous model structure identification and variable selection in generalized partial linear varying coefficient models with longitudinal data," Statistical Papers, Springer, vol. 60(5), pages 1649-1676, October.
    3. Lin, Fangzheng & Tang, Yanlin & Zhu, Zhongyi, 2020. "Weighted quantile regression in varying-coefficient model with longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 145(C).
    4. Qin, Guoyou & Zhang, Jiajia & Zhu, Zhongyi, 2016. "Simultaneous mean and covariance estimation of partially linear models for longitudinal data with missing responses and covariate measurement error," Computational Statistics & Data Analysis, Elsevier, vol. 96(C), pages 24-39.
    5. Yujing Shao & Lei Wang, 2022. "Generalized partial linear models with nonignorable dropouts," Metrika: International Journal for Theoretical and Applied Statistics, Springer, vol. 85(2), pages 223-252, February.
    6. Mao, Jie & Zhu, Zhongyi & Fung, Wing K., 2011. "Joint estimation of mean-covariance model for longitudinal data with basis function approximations," Computational Statistics & Data Analysis, Elsevier, vol. 55(2), pages 983-992, February.
    7. Yehua Li & Yongtao Guan, 2014. "Functional Principal Component Analysis of Spatiotemporal Point Processes With Applications in Disease Surveillance," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 109(507), pages 1205-1215, September.
    8. Kangning Wang & Xiaofei Sun, 2020. "Efficient parameter estimation and variable selection in partial linear varying coefficient quantile regression model with longitudinal data," Statistical Papers, Springer, vol. 61(3), pages 967-995, June.

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