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Spontaneous travelling cortical waves gate perception in behaving primates

Author

Listed:
  • Zachary W. Davis

    (The Salk Institute for Biological Studies)

  • Lyle Muller

    (The Salk Institute for Biological Studies
    Western University
    Western University
    CNRS, Aix-Marseille Université)

  • Julio Martinez-Trujillo

    (Western University
    Western University
    Western University)

  • Terrence Sejnowski

    (The Salk Institute for Biological Studies)

  • John H. Reynolds

    (The Salk Institute for Biological Studies)

Abstract

Perceptual sensitivity varies from moment to moment. One potential source of this variability is spontaneous fluctuations in cortical activity that can travel as waves1. Spontaneous travelling waves have been reported during anaesthesia2–7, but it is not known whether they have a role during waking perception. Here, using newly developed analytic techniques to characterize the moment-to-moment dynamics of noisy multielectrode data, we identify spontaneous waves of activity in the extrastriate visual cortex of awake, behaving marmosets (Callithrix jacchus). In monkeys trained to detect faint visual targets, the timing and position of spontaneous travelling waves before target onset predicted the magnitude of target-evoked activity and the likelihood of target detection. By contrast, spatially disorganized fluctuations of neural activity were much less predictive. These results reveal an important role for spontaneous travelling waves in sensory processing through the modulation of neural and perceptual sensitivity.

Suggested Citation

  • Zachary W. Davis & Lyle Muller & Julio Martinez-Trujillo & Terrence Sejnowski & John H. Reynolds, 2020. "Spontaneous travelling cortical waves gate perception in behaving primates," Nature, Nature, vol. 587(7834), pages 432-436, November.
    • Handle: RePEc:nat:nature:v:587:y:2020:i:7834:d:10.1038_s41586-020-2802-y
    DOI: 10.1038/s41586-020-2802-y
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    Citations

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    Cited by:

    1. Adeeti Aggarwal & Connor Brennan & Jennifer Luo & Helen Chung & Diego Contreras & Max B. Kelz & Alex Proekt, 2022. "Visual evoked feedforward–feedback traveling waves organize neural activity across the cortical hierarchy in mice," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    2. Boaretto, Bruno R.R. & Budzinski, Roberto C. & Rossi, Kalel L. & Masoller, Cristina & Macau, Elbert E.N., 2023. "Spatial permutation entropy distinguishes resting brain states," Chaos, Solitons & Fractals, Elsevier, vol. 171(C).
    3. Patrick Jendritza & Frederike J. Klein & Pascal Fries, 2023. "Multi-area recordings and optogenetics in the awake, behaving marmoset," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    4. Erfan Zabeh & Nicholas C. Foley & Joshua Jacobs & Jacqueline P. Gottlieb, 2023. "Beta traveling waves in monkey frontal and parietal areas encode recent reward history," Nature Communications, Nature, vol. 14(1), pages 1-12, December.
    5. Georgios Spyropoulos & Matteo Saponati & Jarrod Robert Dowdall & Marieke Louise Schölvinck & Conrado Arturo Bosman & Bruss Lima & Alina Peter & Irene Onorato & Johanna Klon-Lipok & Rasmus Roese & Serg, 2022. "Spontaneous variability in gamma dynamics described by a damped harmonic oscillator driven by noise," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    6. Yuqi Liang & Junhao Liang & Chenchen Song & Mianxin Liu & Thomas Knöpfel & Pulin Gong & Changsong Zhou, 2023. "Complexity of cortical wave patterns of the wake mouse cortex," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    7. Anirban Das & Alec G. Sheffield & Anirvan S. Nandy & Monika P. Jadi, 2024. "Brain-state mediated modulation of inter-laminar dependencies in visual cortex," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    8. Dominik P. Koller & Michael Schirner & Petra Ritter, 2024. "Human connectome topology directs cortical traveling waves and shapes frequency gradients," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
    9. Gabriel B. Benigno & Roberto C. Budzinski & Zachary W. Davis & John H. Reynolds & Lyle Muller, 2023. "Waves traveling over a map of visual space can ignite short-term predictions of sensory input," Nature Communications, Nature, vol. 14(1), pages 1-14, December.

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