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Basis of catalytic assembly of the mitotic checkpoint complex

Author

Listed:
  • Alex C. Faesen

    (Max-Planck Institute of Molecular Physiology)

  • Maria Thanasoula

    (Max-Planck Institute of Molecular Physiology)

  • Stefano Maffini

    (Max-Planck Institute of Molecular Physiology)

  • Claudia Breit

    (Max-Planck Institute of Molecular Physiology)

  • Franziska Müller

    (Max-Planck Institute of Molecular Physiology)

  • Suzan van Gerwen

    (Max-Planck Institute of Molecular Physiology)

  • Tanja Bange

    (Max-Planck Institute of Molecular Physiology)

  • Andrea Musacchio

    (Max-Planck Institute of Molecular Physiology
    Centre for Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitätsstraße)

Abstract

The near-complete in vitro reconstitution of the mitotic spindle assembly checkpoint reveals how the assembly of its effector, the mitotic checkpoint complex, is catalysed.

Suggested Citation

  • Alex C. Faesen & Maria Thanasoula & Stefano Maffini & Claudia Breit & Franziska Müller & Suzan van Gerwen & Tanja Bange & Andrea Musacchio, 2017. "Basis of catalytic assembly of the mitotic checkpoint complex," Nature, Nature, vol. 542(7642), pages 498-502, February.
  • Handle: RePEc:nat:nature:v:542:y:2017:i:7642:d:10.1038_nature21384
    DOI: 10.1038/nature21384
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    Citations

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    Cited by:

    1. Chu Chen & Valentina Piano & Amal Alex & Simon J. Y. Han & Pim J. Huis in ’t Veld & Babhrubahan Roy & Daniel Fergle & Andrea Musacchio & Ajit P. Joglekar, 2023. "The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    2. Elyse S. Fischer & Conny W. H. Yu & Johannes F. Hevler & Stephen H. McLaughlin & Sarah L. Maslen & Albert J. R. Heck & Stefan M. V. Freund & David Barford, 2022. "Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    3. Christian Hoischen & Sibel Yavas & Thorsten Wohland & Stephan Diekmann, 2018. "CENP-C/H/I/K/M/T/W/N/L and hMis12 but not CENP-S/X participate in complex formation in the nucleoplasm of living human interphase cells outside centromeres," PLOS ONE, Public Library of Science, vol. 13(3), pages 1-26, March.
    4. Fridolin Gross & Paolo Bonaiuti & Silke Hauf & Andrea Ciliberto, 2018. "Implications of alternative routes to APC/C inhibition by the mitotic checkpoint complex," PLOS Computational Biology, Public Library of Science, vol. 14(9), pages 1-19, September.

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