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Mechanism of super-assembly of respiratory complexes III and IV

Author

Listed:
  • Sara Cogliati

    (Centro Nacional de Investigaciones Cardiovasculares Carlos III)

  • Enrique Calvo

    (Centro Nacional de Investigaciones Cardiovasculares Carlos III)

  • Marta Loureiro

    (Centro Nacional de Investigaciones Cardiovasculares Carlos III)

  • Adela M. Guaras

    (Centro Nacional de Investigaciones Cardiovasculares Carlos III)

  • Rocio Nieto-Arellano

    (Centro Nacional de Investigaciones Cardiovasculares Carlos III)

  • Carolina Garcia-Poyatos

    (Centro Nacional de Investigaciones Cardiovasculares Carlos III
    Institute of Anatomy, University of Bern)

  • Iakes Ezkurdia

    (Centro Nacional de Investigaciones Cardiovasculares Carlos III)

  • Nadia Mercader

    (Centro Nacional de Investigaciones Cardiovasculares Carlos III
    Institute of Anatomy, University of Bern)

  • Jesús Vázquez

    (Centro Nacional de Investigaciones Cardiovasculares Carlos III)

  • José Antonio Enriquez

    (Centro Nacional de Investigaciones Cardiovasculares Carlos III
    Universidad de Zaragoza)

Abstract

SCAF1 is always required for the interaction between the respiratory chain complexes III and IV, and in animals carrying only the short isoform of SCAF1, the respirasome is absent in most tissues, with the exception of heart and skeletal muscle, where COX7A2 is present instead of SCAF1.

Suggested Citation

  • Sara Cogliati & Enrique Calvo & Marta Loureiro & Adela M. Guaras & Rocio Nieto-Arellano & Carolina Garcia-Poyatos & Iakes Ezkurdia & Nadia Mercader & Jesús Vázquez & José Antonio Enriquez, 2016. "Mechanism of super-assembly of respiratory complexes III and IV," Nature, Nature, vol. 539(7630), pages 579-582, November.
  • Handle: RePEc:nat:nature:v:539:y:2016:i:7630:d:10.1038_nature20157
    DOI: 10.1038/nature20157
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    Cited by:

    1. Ami Kobayashi & Kotaro Azuma & Toshihiko Takeiwa & Toshimori Kitami & Kuniko Horie & Kazuhiro Ikeda & Satoshi Inoue, 2023. "A FRET-based respirasome assembly screen identifies spleen tyrosine kinase as a target to improve muscle mitochondrial respiration and exercise performance in mice," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    2. Fangzhu Han & Yiqi Hu & Mengchen Wu & Zhaoxiang He & Hongtao Tian & Long Zhou, 2023. "Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae," Nature Communications, Nature, vol. 14(1), pages 1-13, December.

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