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Identification of carbohydrate anomers using ion mobility–mass spectrometry

Author

Listed:
  • J. Hofmann

    (Fritz Haber Institute of the Max Planck Society
    Institute for Chemistry and Biochemistry, Free University Berlin)

  • H. S. Hahm

    (Max Planck Institute of Colloids and Interfaces
    Institute for Chemistry and Biochemistry, Free University Berlin)

  • P. H. Seeberger

    (Max Planck Institute of Colloids and Interfaces
    Institute for Chemistry and Biochemistry, Free University Berlin)

  • K. Pagel

    (Fritz Haber Institute of the Max Planck Society
    Institute for Chemistry and Biochemistry, Free University Berlin)

Abstract

The branched structure and stereoisomerism of carbohydrates make them difficult to analyse; here, ion mobility–mass spectrometry is used to distinguish unambiguously between synthetic trisaccharides that differ in connectivity or configuration.

Suggested Citation

  • J. Hofmann & H. S. Hahm & P. H. Seeberger & K. Pagel, 2015. "Identification of carbohydrate anomers using ion mobility–mass spectrometry," Nature, Nature, vol. 526(7572), pages 241-244, October.
    • Handle: RePEc:nat:nature:v:526:y:2015:i:7572:d:10.1038_nature15388
    DOI: 10.1038/nature15388
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    Cited by:

    1. Xiaoyu Zhou & Zhuofan Wang & Jingjin Fan & Zheng Ouyang, 2023. "High-resolution separation of bioisomers using ion cloud profiling," Nature Communications, Nature, vol. 14(1), pages 1-6, December.
    2. Leïla Bechtella & Jin Chunsheng & Kerstin Fentker & Güney R. Ertürk & Marc Safferthal & Łukasz Polewski & Michael Götze & Simon Y. Graeber & Gaël M. Vos & Weston B. Struwe & Marcus A. Mall & Philipp M, 2024. "Ion mobility-tandem mass spectrometry of mucin-type O-glycans," Nature Communications, Nature, vol. 15(1), pages 1-10, December.
    3. Minmin Li & Yuting Xiong & Yuchen Cao & Chen Zhang & Yuting Li & Hanwen Ning & Fan Liu & Han Zhou & Xiaonong Li & Xianlong Ye & Yue Pang & Jiaming Zhang & Xinmiao Liang & Guangyan Qing, 2023. "Identification of tagged glycans with a protein nanopore," Nature Communications, Nature, vol. 14(1), pages 1-12, December.

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