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Reproducibility crisis: Blame it on the antibodies

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  • Monya Baker

    (Monya Baker writes and edits for Nature in San Francisco, California.)

Abstract

Antibodies are the workhorses of biological experiments, but they are littering the field with false findings. A few evangelists are pushing for change.

Suggested Citation

  • Monya Baker, 2015. "Reproducibility crisis: Blame it on the antibodies," Nature, Nature, vol. 521(7552), pages 274-276, May.
    • Handle: RePEc:nat:nature:v:521:y:2015:i:7552:d:10.1038_521274a
    DOI: 10.1038/521274a
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    Cited by:

    1. Bettina Bert & Céline Heinl & Justyna Chmielewska & Franziska Schwarz & Barbara Grune & Andreas Hensel & Matthias Greiner & Gilbert Schönfelder, 2019. "Refining animal research: The Animal Study Registry," PLOS Biology, Public Library of Science, vol. 17(10), pages 1-12, October.
    2. Adrian C. D. Fuchs, 2023. "Specific, sensitive and quantitative protein detection by in-gel fluorescence," Nature Communications, Nature, vol. 14(1), pages 1-10, December.
    3. Edward P. Harvey & Jung-Eun Shin & Meredith A. Skiba & Genevieve R. Nemeth & Joseph D. Hurley & Alon Wellner & Ada Y. Shaw & Victor G. Miranda & Joseph K. Min & Chang C. Liu & Debora S. Marks & Andrew, 2022. "An in silico method to assess antibody fragment polyreactivity," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
    4. Linsley Kelly & Keith E. Maier & Amy Yan & Matthew Levy, 2021. "A comparative analysis of cell surface targeting aptamers," Nature Communications, Nature, vol. 12(1), pages 1-14, December.

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