IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v468y2010i7324d10.1038_nature09537.html
   My bibliography  Save this article

Acid sensing by the Drosophila olfactory system

Author

Listed:
  • Minrong Ai

    (Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, New York University, School of Medicine)

  • Soohong Min

    (Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, New York University, School of Medicine)

  • Yael Grosjean

    (Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne
    Present addresses: Centre des Sciences du Goût et de l’Alimentation, UMR-6265 CNRS, UMR-1324 INRA, Université de Bourgogne, 6 Boulevard Gabriel, 21000 Dijon, France (Y.G.); Université Paris Diderot – Paris 7, 16 rue Marguerite Duras, 75013 Paris, France (C.L.).)

  • Charlotte Leblanc

    (Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, New York University, School of Medicine
    Present addresses: Centre des Sciences du Goût et de l’Alimentation, UMR-6265 CNRS, UMR-1324 INRA, Université de Bourgogne, 6 Boulevard Gabriel, 21000 Dijon, France (Y.G.); Université Paris Diderot – Paris 7, 16 rue Marguerite Duras, 75013 Paris, France (C.L.).)

  • Rati Bell

    (Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne)

  • Richard Benton

    (Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne)

  • Greg S. B. Suh

    (Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, New York University, School of Medicine)

Abstract

Sensing the odour of acid We are familiar with the unpleasant and often irritating odour associated with acids, but whereas acid receptors are known to underlie the detection of sour tastes, no acid-sensing neurons were known in the olfactory system. Greg Suh and colleagues now report the identification of such neurons in the olfactory system of the fruitfly, Drosophila melanogaster. Acid sensing also requires the transmembrane protein IR64a to be expressed in those neurons. IR64a is not sufficient by itself to determine acid recognition, but its requirement is the first known function for a member of the recently discovered ionotropic receptor family of putative odorant receptors.

Suggested Citation

  • Minrong Ai & Soohong Min & Yael Grosjean & Charlotte Leblanc & Rati Bell & Richard Benton & Greg S. B. Suh, 2010. "Acid sensing by the Drosophila olfactory system," Nature, Nature, vol. 468(7324), pages 691-695, December.
    • Handle: RePEc:nat:nature:v:468:y:2010:i:7324:d:10.1038_nature09537
    DOI: 10.1038/nature09537
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature09537
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature09537?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Thomas A. Verschut & Renny Ng & Nicolas P. Doubovetzky & Guillaume Calvez & Jan L. Sneep & Adriaan J. Minnaard & Chih-Ying Su & Mikael A. Carlsson & Bregje Wertheim & Jean-Christophe Billeter, 2023. "Aggregation pheromones have a non-linear effect on oviposition behavior in Drosophila melanogaster," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    2. Liangyu Tao & Samuel P. Wechsler & Vikas Bhandawat, 2023. "Sensorimotor transformation underlying odor-modulated locomotion in walking Drosophila," Nature Communications, Nature, vol. 14(1), pages 1-22, December.
    3. Raquel Álvarez-Ocaña & Michael P. Shahandeh & Vijayaditya Ray & Thomas O. Auer & Nicolas Gompel & Richard Benton, 2023. "Odor-regulated oviposition behavior in an ecological specialist," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    4. Javier J How & Saket Navlakha & Sreekanth H Chalasani, 2021. "Neural network features distinguish chemosensory stimuli in Caenorhabditis elegans," PLOS Computational Biology, Public Library of Science, vol. 17(11), pages 1-38, November.
    5. J Roman Arguello & Carolina Sellanes & Yann Ru Lou & Robert A Raguso, 2013. "Can Yeast (S. cerevisiae) Metabolic Volatiles Provide Polymorphic Signaling?," PLOS ONE, Public Library of Science, vol. 8(8), pages 1-12, August.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:468:y:2010:i:7324:d:10.1038_nature09537. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.