IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v448y2007i7154d10.1038_nature06006.html
   My bibliography  Save this article

The JAZ family of repressors is the missing link in jasmonate signalling

Author

Listed:
  • A. Chini

    (Departamento de Genética Molecular de Plantas and,)

  • S. Fonseca

    (Departamento de Genética Molecular de Plantas and,)

  • G. Fernández

    (Departamento de Genética Molecular de Plantas and,)

  • B. Adie

    (Departamento de Genética Molecular de Plantas and,)

  • J. M. Chico

    (Departamento de Genética Molecular de Plantas and,)

  • O. Lorenzo

    (Departamento de Genética Molecular de Plantas and,
    Present address: Dpto. de Fisiología Vegetal. Centro Hispano-Luso de Investigaciones Agrarias (CIALE), Facultad de Biología, Universidad de Salamanca, Plaza de los Doctores de la Reina s/n, 37007 Salamanca, Spain.)

  • G. García-Casado

    (Unidad de Genómica, Centro Nacional de Biotecnología-CSIC, Campus Universidad Autónoma, 28049 Madrid, Spain)

  • I. López-Vidriero

    (Unidad de Genómica, Centro Nacional de Biotecnología-CSIC, Campus Universidad Autónoma, 28049 Madrid, Spain)

  • F. M. Lozano

    (División de Genética and Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain)

  • M. R. Ponce

    (División de Genética and Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain)

  • J. L. Micol

    (División de Genética and Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain)

  • R. Solano

    (Departamento de Genética Molecular de Plantas and,
    Unidad de Genómica, Centro Nacional de Biotecnología-CSIC, Campus Universidad Autónoma, 28049 Madrid, Spain)

Abstract

Jasmonates are essential phytohormones for plant development and survival. However, the molecular details of their signalling pathway remain largely unknown. The identification more than a decade ago of COI1 as an F-box protein suggested the existence of a repressor of jasmonate responses that is targeted by the SCFCOI1 complex for proteasome degradation in response to jasmonate. Here we report the identification of JASMONATE-INSENSITIVE 3 (JAI3) and a family of related proteins named JAZ (jasmonate ZIM-domain), in Arabidopsis thaliana. Our results demonstrate that JAI3 and other JAZs are direct targets of the SCFCOI1 E3 ubiquitin ligase and jasmonate treatment induces their proteasome degradation. Moreover, JAI3 negatively regulates the key transcriptional activator of jasmonate responses, MYC2. The JAZ family therefore represents the molecular link between the two previously known steps in the jasmonate pathway. Furthermore, we demonstrate the existence of a regulatory feed-back loop involving MYC2 and JAZ proteins, which provides a mechanistic explanation for the pulsed response to jasmonate and the subsequent desensitization of the cell.

Suggested Citation

  • A. Chini & S. Fonseca & G. Fernández & B. Adie & J. M. Chico & O. Lorenzo & G. García-Casado & I. López-Vidriero & F. M. Lozano & M. R. Ponce & J. L. Micol & R. Solano, 2007. "The JAZ family of repressors is the missing link in jasmonate signalling," Nature, Nature, vol. 448(7154), pages 666-671, August.
    • Handle: RePEc:nat:nature:v:448:y:2007:i:7154:d:10.1038_nature06006
    DOI: 10.1038/nature06006
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature06006
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature06006?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Hiroyuki Iida & Ari Pekka Mähönen & Gerd Jürgens & Shinobu Takada, 2023. "Epidermal injury-induced derepression of key regulator ATML1 in newly exposed cells elicits epidermis regeneration," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    2. Yuki Furuta & Haruka Yamamoto & Takeshi Hirakawa & Akira Uemura & Margaret Anne Pelayo & Hideaki Iimura & Naoya Katagiri & Noriko Takeda-Kamiya & Kie Kumaishi & Makoto Shirakawa & Sumie Ishiguro & Yas, 2024. "Petal abscission is promoted by jasmonic acid-induced autophagy at Arabidopsis petal bases," Nature Communications, Nature, vol. 15(1), pages 1-24, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:448:y:2007:i:7154:d:10.1038_nature06006. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.