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Lateral gene transfer and the nature of bacterial innovation

Author

Listed:
  • Howard Ochman

    (University of Arizona)

  • Jeffrey G. Lawrence

    (University of Pittsburgh)

  • Eduardo A. Groisman

    (Howard Hughes Medical Institute, Washington University School of Medicine)

Abstract

Unlike eukaryotes, which evolve principally through the modification of existing genetic information, bacteria have obtained a significant proportion of their genetic diversity through the acquisition of sequences from distantly related organisms. Horizontal gene transfer produces extremely dynamic genomes in which substantial amounts of DNA are introduced into and deleted from the chromosome. These lateral transfers have effectively changed the ecological and pathogenic character of bacterial species.

Suggested Citation

  • Howard Ochman & Jeffrey G. Lawrence & Eduardo A. Groisman, 2000. "Lateral gene transfer and the nature of bacterial innovation," Nature, Nature, vol. 405(6784), pages 299-304, May.
    • Handle: RePEc:nat:nature:v:405:y:2000:i:6784:d:10.1038_35012500
    DOI: 10.1038/35012500
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    Citations

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    Cited by:

    1. Rajeev K Azad & Jeffrey G Lawrence, 2005. "Use of Artificial Genomes in Assessing Methods for Atypical Gene Detection," PLOS Computational Biology, Public Library of Science, vol. 1(6), pages 1-13, November.
    2. Ernestina Hauptfeld & Nikolaos Pappas & Sandra Iwaarden & Basten L. Snoek & Andrea Aldas-Vargas & Bas E. Dutilh & F. A. Bastiaan Meijenfeldt, 2024. "Integrating taxonomic signals from MAGs and contigs improves read annotation and taxonomic profiling of metagenomes," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    3. Rohan Maddamsetti & Yi Yao & Teng Wang & Junheng Gao & Vincent T. Huang & Grayson S. Hamrick & Hye-In Son & Lingchong You, 2024. "Duplicated antibiotic resistance genes reveal ongoing selection and horizontal gene transfer in bacteria," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    4. Lashin, Sergey A. & Matushkin, Yury G. & Suslov, Valentin V. & Kolchanov, Nikolay A., 2012. "Computer modeling of genome complexity variation trends in prokaryotic communities under varying habitat conditions," Ecological Modelling, Elsevier, vol. 224(1), pages 124-129.
    5. Ari J S Ferreira & Rania Siam & João C Setubal & Ahmed Moustafa & Ahmed Sayed & Felipe S Chambergo & Adam S Dawe & Mohamed A Ghazy & Hazem Sharaf & Amged Ouf & Intikhab Alam & Alyaa M Abdel-Haleem & H, 2014. "Core Microbial Functional Activities in Ocean Environments Revealed by Global Metagenomic Profiling Analyses," PLOS ONE, Public Library of Science, vol. 9(6), pages 1-11, June.
    6. Nara Figueroa-Bossi & Rocío Fernández-Fernández & Patricia Kerboriou & Philippe Bouloc & Josep Casadesús & María Antonia Sánchez-Romero & Lionello Bossi, 2024. "Transcription-driven DNA supercoiling counteracts H-NS-mediated gene silencing in bacterial chromatin," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    7. João F Matias Rodrigues & Andreas Wagner, 2009. "Evolutionary Plasticity and Innovations in Complex Metabolic Reaction Networks," PLOS Computational Biology, Public Library of Science, vol. 5(12), pages 1-11, December.
    8. Benedetta Tuvo & Michela Scarpaci & Sara Bracaloni & Enrica Esposito & Anna Laura Costa & Martina Ioppolo & Beatrice Casini, 2023. "Microplastics and Antibiotic Resistance: The Magnitude of the Problem and the Emerging Role of Hospital Wastewater," IJERPH, MDPI, vol. 20(10), pages 1-14, May.
    9. Elia Salibi & Benedikt Peter & Petra Schwille & Hannes Mutschler, 2023. "Periodic temperature changes drive the proliferation of self-replicating RNAs in vesicle populations," Nature Communications, Nature, vol. 14(1), pages 1-9, December.
    10. Yi-Long Hao & Gang Li & Zu-Fei Xiao & Ning Liu & Muhammad Azeem & Yi Zhao & Yao-Yang Xu & Xin-Wei Yu, 2021. "Distribution and Influence on the Microbial Ecological Relationship of Antibiotic Resistance Genes in Soil at a Watershed Scale," Sustainability, MDPI, vol. 13(17), pages 1-16, August.
    11. Blath, Jochen & Tóbiás, András, 2021. "The interplay of dormancy and transfer in bacterial populations: Invasion, fixation and coexistence regimes," Theoretical Population Biology, Elsevier, vol. 139(C), pages 18-49.
    12. Eremwanarue Aibuedefe Osagie & Shittu Hakeem Olalekan & Eremwanarue Aibuedefe Osagie, 2019. "Multiple Drug Resistance- A Fast-Growing Threat," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 21(2), pages 15715-15726, September.
    13. Tazzyman, Samuel J. & Bonhoeffer, Sebastian, 2013. "Fixation probability of mobile genetic elements such as plasmids," Theoretical Population Biology, Elsevier, vol. 90(C), pages 49-55.
    14. Jennifer Kuzma & James Romanchek & Adam Kokotovich, 2008. "Upstream Oversight Assessment for Agrifood Nanotechnology: A Case Studies Approach," Risk Analysis, John Wiley & Sons, vol. 28(4), pages 1081-1098, August.
    15. Wu, Zuo-Bing, 2010. "Global transposable characteristics in the complete DNA sequence of the yeast," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 389(24), pages 5698-5705.
    16. Aletheia Atzinger & Jeffrey G Lawrence, 2020. "Selection for ancient periodic motifs that do not impart DNA bending," PLOS Genetics, Public Library of Science, vol. 16(10), pages 1-25, October.
    17. Brian D. Huang & Dowan Kim & Yongjoon Yu & Corey J. Wilson, 2024. "Engineering intelligent chassis cells via recombinase-based MEMORY circuits," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
    18. Jenny Wachter & Britney Cheff & Chad Hillman & Valentina Carracoi & David W. Dorward & Craig Martens & Kent Barbian & Glenn Nardone & L. Renee Olano & Margie Kinnersley & Patrick R. Secor & Patricia A, 2023. "Coupled induction of prophage and virulence factors during tick transmission of the Lyme disease spirochete," Nature Communications, Nature, vol. 14(1), pages 1-18, December.

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