IDEAS home Printed from https://ideas.repec.org/a/nat/nathum/v8y2024i12d10.1038_s41562-024-02000-9.html
   My bibliography  Save this article

Executive function in children with neurodevelopmental conditions: a systematic review and meta-analysis

Author

Listed:
  • Ayesha K. Sadozai

    (University of Sydney
    University of Sydney)

  • Carter Sun

    (University of Sydney
    University of Sydney
    University of Sydney)

  • Eleni A. Demetriou

    (University of Sydney
    University of Sydney)

  • Amit Lampit

    (University of Melbourne)

  • Martha Munro

    (University of Sydney
    University of Sydney)

  • Nina Perry

    (University of Sydney
    University of Sydney)

  • Kelsie A. Boulton

    (University of Sydney
    University of Sydney)

  • Adam J. Guastella

    (University of Sydney
    University of Sydney)

Abstract

Executive function (EF) delays are well documented in paediatric neurodevelopmental conditions (NDCs). There is no consensus about whether EF delay represents a transdiagnostic feature of NDCs. This systematic review and meta-analysis synthesized 180 studies reporting two or more NDC comparisons on EF, examined differences between NDCs, and the moderating effects of gender, age, publication year, DSM editions and assessment types. Studies using established EF measures across seven domains (attention, fluency, set-shifting, set-switching, response inhibition, planning and working memory) in participants under 18 were included. Summary effects were compared: (1) for all reported NDCs relative to control, (2) for each individual NDC relative to control and (3) between NDC groups. Results confirmed that EF delay was a transdiagnostic feature of neurodevelopmental delay, with a moderate effect size of delay across all NDCs (g = 0.56, 95% confidence interval (CI) 0.49–0.63) compared with control. This effect increased with comorbidities (g = 0.72, 95% CI 0.59–0.86), DSM-5 criteria and informant measures. Comparisons between NDCs revealed few differences: children with tic disorders (TD) showed smaller EF delays, children with attention-deficit/hyperactivity disorder (ADHD) showed larger delays in attention, response inhibition, planning and working memory compared with TD and specific learning disorders, while children with autism spectrum disorders showed greater delays on set-switching compared with ADHD. Findings support transdiagnostic models of neurodevelopment to further a developmentally sensitive science that can reveal how EF delays contribute to brain circuitry, symptom profiles and functioning, and ultimately support early interventions and outcomes for all children with NDCs.

Suggested Citation

  • Ayesha K. Sadozai & Carter Sun & Eleni A. Demetriou & Amit Lampit & Martha Munro & Nina Perry & Kelsie A. Boulton & Adam J. Guastella, 2024. "Executive function in children with neurodevelopmental conditions: a systematic review and meta-analysis," Nature Human Behaviour, Nature, vol. 8(12), pages 2357-2366, December.
  • Handle: RePEc:nat:nathum:v:8:y:2024:i:12:d:10.1038_s41562-024-02000-9
    DOI: 10.1038/s41562-024-02000-9
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41562-024-02000-9
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1038/s41562-024-02000-9?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Alessandro Liberati & Douglas G Altman & Jennifer Tetzlaff & Cynthia Mulrow & Peter C Gøtzsche & John P A Ioannidis & Mike Clarke & P J Devereaux & Jos Kleijnen & David Moher, 2009. "The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-28, July.
    2. Matthew J Page & Joanne E McKenzie & Patrick M Bossuyt & Isabelle Boutron & Tammy C Hoffmann & Cynthia D Mulrow & Larissa Shamseer & Jennifer M Tetzlaff & Elie A Akl & Sue E Brennan & Roger Chou & Jul, 2021. "The PRISMA 2020 statement: An updated guideline for reporting systematic reviews," PLOS Medicine, Public Library of Science, vol. 18(3), pages 1-15, March.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Sónia Rolland Sobral, 2021. "Teaching and Learning to Program: Umbrella Review of Introductory Programming in Higher Education," Mathematics, MDPI, vol. 9(15), pages 1-23, July.
    2. Aiyar, Ria & Due, Clemence & Taylor, Amanda M. & Sawyer, Alyssa C.P., 2023. "The wellbeing and support experiences of parents and caregivers from South and Southeast Asian refugee backgrounds during the First 2000 Days: A systematic review," Children and Youth Services Review, Elsevier, vol. 155(C).
    3. Carmen Díaz-López & Alessandra Bonoli & María Martín-Morales & Montserrat Zamorano, 2021. "Analysis of the Scientific Evolution of the Circular Economy Applied to Construction and Demolition Waste," Sustainability, MDPI, vol. 13(16), pages 1-22, August.
    4. Dahlan Abdullah & Nurul Husna Zabidi & Dina Nurzafira Zulzamzuri & Ahmad Redhuan Abu Bakar & Siti Aisyah Tumin & Teku Zariff Zaeimoedin, 2024. "Unpacking the Inflation Basket: A Systematic Literature Review of Key Determinants of Rising Food Prices and their Global Impact," International Journal of Research and Innovation in Social Science, International Journal of Research and Innovation in Social Science (IJRISS), vol. 8(9), pages 706-713, September.
    5. Gourlan, Mathieu & Ricupero, Sarah & Carayol, Marion & Cousson-Gélie, Florence, 2023. "Efficacy of theory-based interventions aimed at reducing binge drinking in adolescents: A systematic review and meta-analysis of randomised controlled trials," Social Science & Medicine, Elsevier, vol. 317(C).
    6. Ludoviko Zirimenya & Fatima Mahmud-Ajeigbe & Ruth McQuillan & You Li, 2020. "A systematic review and meta-analysis to assess the association between urogenital schistosomiasis and HIV/AIDS infection," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 14(6), pages 1-13, June.
    7. Trang Nguyen & Sara Holton & Thach Tran & Jane Fisher, 2019. "Informal mental health interventions for people with severe mental illness in low and lower middle-income countries: A systematic review of effectiveness," International Journal of Social Psychiatry, , vol. 65(3), pages 194-206, May.
    8. Alessandro Concari & Gerjo Kok & Pim Martens, 2020. "A Systematic Literature Review of Concepts and Factors Related to Pro-Environmental Consumer Behaviour in Relation to Waste Management Through an Interdisciplinary Approach," Sustainability, MDPI, vol. 12(11), pages 1-50, May.
    9. Damiano Pizzol & Mike Trott & Igor Grabovac & Mario Antunes & Anna Claudia Colangelo & Simona Ippoliti & Cristian Petre Ilie & Anne Carrie & Nicola Veronese & Lee Smith, 2021. "Laparoscopy in Low-Income Countries: 10-Year Experience and Systematic Literature Review," IJERPH, MDPI, vol. 18(11), pages 1-11, May.
    10. Boglárka Anna Éliás & Attila Jámbor, 2021. "Food Security and COVID-19: A Systematic Review of the First-Year Experience," Sustainability, MDPI, vol. 13(9), pages 1-18, May.
    11. Omoyele, Olalekan & Hoffmann, Maximilian & Koivisto, Matti & Larrañeta, Miguel & Weinand, Jann Michael & Linßen, Jochen & Stolten, Detlef, 2024. "Increasing the resolution of solar and wind time series for energy system modeling: A review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 189(PB).
    12. Alessandro Margherita & Emanuele Banchi & Alfredo Biffi & Gianluca di Castri & Rocco Morelli, 2022. "Beyond Total Cost Management (TCM) to Systemic Value Management (SVM): Transformational Trends and a Research Manifesto for an Evolving Discipline," Sustainability, MDPI, vol. 14(19), pages 1-16, October.
    13. Stefano D’Angelo & Angelo Cavallo & Antonio Ghezzi & Francesco Di Lorenzo, 2024. "Understanding corporate entrepreneurship in the digital age: a review and research agenda," Review of Managerial Science, Springer, vol. 18(12), pages 3719-3774, December.
    14. Cala, Anggie & Maturana-Córdoba, Aymer & Soto-Verjel, Joseph, 2023. "Exploring the pretreatments' influence on pressure reverse osmosis: PRISMA review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 188(C).
    15. Fabio Magnacca & Riccardo Giannetti, 2024. "Management accounting and new product development: a systematic literature review and future research directions," Journal of Management & Governance, Springer;Accademia Italiana di Economia Aziendale (AIDEA), vol. 28(2), pages 651-685, June.
    16. Michael Masaracchio & William J Hanney & Xinliang Liu & Morey Kolber & Kaitlin Kirker, 2017. "Timing of rehabilitation on length of stay and cost in patients with hip or knee joint arthroplasty: A systematic review with meta-analysis," PLOS ONE, Public Library of Science, vol. 12(6), pages 1-22, June.
    17. Evans, Rhiannon & White, James & Turley, Ruth & Slater, Thomas & Morgan, Helen & Strange, Heather & Scourfield, Jonathan, 2017. "Comparison of suicidal ideation, suicide attempt and suicide in children and young people in care and non-care populations: Systematic review and meta-analysis of prevalence," Children and Youth Services Review, Elsevier, vol. 82(C), pages 122-129.
    18. Ming Shan & Yu-Shan Li & Bon-Gang Hwang & Jia-En Chua, 2021. "Productivity Metrics and Its Implementations in Construction Projects: A Case Study of Singapore," Sustainability, MDPI, vol. 13(21), pages 1-19, November.
    19. Susca, T. & Zanghirella, F. & Colasuonno, L. & Del Fatto, V., 2022. "Effect of green wall installation on urban heat island and building energy use: A climate-informed systematic literature review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 159(C).
    20. Alexander P. L. Martindale & Carrie D. Llewellyn & Richard O. Visser & Benjamin Ng & Victoria Ngai & Aditya U. Kale & Lavinia Ferrante Ruffano & Robert M. Golub & Gary S. Collins & David Moher & Melis, 2024. "Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines," Nature Communications, Nature, vol. 15(1), pages 1-11, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nathum:v:8:y:2024:i:12:d:10.1038_s41562-024-02000-9. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.