IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v1y2010i1d10.1038_ncomms1042.html
   My bibliography  Save this article

Multifunctional nanoparticles as coupled contrast agents

Author

Listed:
  • Yongdong Jin

    (University of Washington, William H Foege Building N530M, Seattle, Washington 98195, USA.)

  • Congxian Jia

    (University of Michigan)

  • Sheng-Wen Huang

    (University of Washington, William H Foege Building N530M, Seattle, Washington 98195, USA.)

  • Matthew O'Donnell

    (University of Washington, William H Foege Building N530M, Seattle, Washington 98195, USA.
    University of Michigan)

  • Xiaohu Gao

    (University of Washington, William H Foege Building N530M, Seattle, Washington 98195, USA.)

Abstract

Engineering compact imaging probes with highly integrated modalities is a key focus in bionanotechnology and will have profound impact on molecular diagnostics, imaging and therapeutics. However, combining multiple components on a nanometre scale to create new imaging modalities unavailable from individual components has proven to be challenging. In this paper, we demonstrate iron oxide and gold-coupled core-shell nanoparticles (NPs) with well-defined structural characteristics (for example, size, shell thickness and core-shell separation) and physical properties (for example, electronic, magnetic, optical, thermal and acoustic). The resulting multifunctional nanoprobes not only offer contrast for electron microscopy, magnetic resonance imaging and scattering-based imaging but, more importantly, enable a new imaging mode, magnetomotive photoacoustic imaging, with remarkable contrast enhancement compared with photoacoustic images using conventional NP contrast agents.

Suggested Citation

  • Yongdong Jin & Congxian Jia & Sheng-Wen Huang & Matthew O'Donnell & Xiaohu Gao, 2010. "Multifunctional nanoparticles as coupled contrast agents," Nature Communications, Nature, vol. 1(1), pages 1-8, December.
    • Handle: RePEc:nat:natcom:v:1:y:2010:i:1:d:10.1038_ncomms1042
    DOI: 10.1038/ncomms1042
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/ncomms1042
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/ncomms1042?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Zhao, Zhenlu & Wu, Haoxi & Li, Chuanping, 2021. "Engineering iron phosphide-on-plasmonic Ag/Au-nanoshells as an efficient cathode catalyst in water splitting for hydrogen production," Energy, Elsevier, vol. 218(C).
    2. Liang Dong & Yun-Jun Xu & Cong Sui & Yang Zhao & Li-Bo Mao & Denis Gebauer & Rose Rosenberg & Jonathan Avaro & Ya-Dong Wu & Huai-Ling Gao & Zhao Pan & Hui-Qin Wen & Xu Yan & Fei Li & Yang Lu & Helmut , 2022. "Highly hydrated paramagnetic amorphous calcium carbonate nanoclusters as an MRI contrast agent," Nature Communications, Nature, vol. 13(1), pages 1-13, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:1:y:2010:i:1:d:10.1038_ncomms1042. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.