Protein kinase N promotes cardiac fibrosis in heart failure by fibroblast-to-myofibroblast conversion
Author
Abstract
Suggested Citation
DOI: 10.1038/s41467-024-52068-0
Download full text from publisher
References listed on IDEAS
- Gabriele G. Schiattarella & Francisco Altamirano & Dan Tong & Kristin M. French & Elisa Villalobos & Soo Young Kim & Xiang Luo & Nan Jiang & Herman I. May & Zhao V. Wang & Theodore M. Hill & Pradeep P, 2019. "Nitrosative stress drives heart failure with preserved ejection fraction," Nature, Nature, vol. 568(7752), pages 351-356, April.
- Lufen Chang & Michael Karin, 2001. "Mammalian MAP kinase signalling cascades," Nature, Nature, vol. 410(6824), pages 37-40, March.
- Neil C. Henderson & Florian Rieder & Thomas A. Wynn, 2020. "Fibrosis: from mechanisms to medicines," Nature, Nature, vol. 587(7835), pages 555-566, November.
- Kazumasa Kanemaru & James Cranley & Daniele Muraro & Antonio M. A. Miranda & Siew Yen Ho & Anna Wilbrey-Clark & Jan Patrick Pett & Krzysztof Polanski & Laura Richardson & Monika Litvinukova & Natsuhik, 2023. "Spatially resolved multiomics of human cardiac niches," Nature, Nature, vol. 619(7971), pages 801-810, July.
Most related items
These are the items that most often cite the same works as this one and are cited by the same works as this one.- Kazunari Iwamoto & Yuki Shindo & Koichi Takahashi, 2016. "Modeling Cellular Noise Underlying Heterogeneous Cell Responses in the Epidermal Growth Factor Signaling Pathway," PLOS Computational Biology, Public Library of Science, vol. 12(11), pages 1-18, November.
- Jonas Engesser & Robin Khatri & Darius P. Schaub & Yu Zhao & Hans-Joachim Paust & Zeba Sultana & Nariaki Asada & Jan-Hendrik Riedel & Varshi Sivayoganathan & Anett Peters & Anna Kaffke & Saskia-Lariss, 2024. "Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritis," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
- Marie Bobowski-Gerard & Clémence Boulet & Francesco P. Zummo & Julie Dubois-Chevalier & Céline Gheeraert & Mohamed Bou Saleh & Jean-Marc Strub & Amaury Farce & Maheul Ploton & Loïc Guille & Jimmy Vand, 2022. "Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis," Nature Communications, Nature, vol. 13(1), pages 1-20, December.
- Yu-Lan Ma & Chun-Yan Kong & Zhen Guo & Ming-Yu Wang & Pan Wang & Fang-Yuan Liu & Dan Yang & Zheng Yang & Qi-Zhu Tang, 2024. "Semaglutide ameliorates cardiac remodeling in male mice by optimizing energy substrate utilization through the Creb5/NR4a1 axis," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
- Mutian Jia & Li Chai & Jie Wang & Mengge Wang & Danhui Qin & Hui Song & Yue Fu & Chunyuan Zhao & Chengjiang Gao & Jihui Jia & Wei Zhao, 2024. "S-nitrosothiol homeostasis maintained by ADH5 facilitates STING-dependent host defense against pathogens," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
- Jiahao Gao & Ya Wang & Xianfu Meng & Xiaoshuang Wang & Fang Han & Hao Xing & Guanglei Lv & Li Zhang & Shiman Wu & Xingwu Jiang & Zhenwei Yao & Xiangming Fang & Jiawen Zhang & Wenbo Bu, 2024. "A FAPα-activated MRI nanoprobe for precise grading diagnosis of clinical liver fibrosis," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
- Fabian Peisker & Maurice Halder & James Nagai & Susanne Ziegler & Nadine Kaesler & Konrad Hoeft & Ronghui Li & Eric M. J. Bindels & Christoph Kuppe & Julia Moellmann & Michael Lehrke & Christian Stopp, 2022. "Mapping the cardiac vascular niche in heart failure," Nature Communications, Nature, vol. 13(1), pages 1-20, December.
- Bin Li & Wen-Wu Bai & Tao Guo & Zhen-Yu Tang & Xue-Jiao Jing & Ti-Chao Shan & Sen Yin & Ying Li & Fu Wang & Mo-Li Zhu & Jun-Xiu Lu & Yong-Ping Bai & Bo Dong & Peng Li & Shuang-Xi Wang, 2024. "Statins improve cardiac endothelial function to prevent heart failure with preserved ejection fraction through upregulating circRNA-RBCK1," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
- Ajita Shree & Musale Krushna Pavan & Hamim Zafar, 2023. "scDREAMER for atlas-level integration of single-cell datasets using deep generative model paired with adversarial classifier," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
- Thomas C Whisenant & David T Ho & Ryan W Benz & Jeffrey S Rogers & Robyn M Kaake & Elizabeth A Gordon & Lan Huang & Pierre Baldi & Lee Bardwell, 2010. "Computational Prediction and Experimental Verification of New MAP Kinase Docking Sites and Substrates Including Gli Transcription Factors," PLOS Computational Biology, Public Library of Science, vol. 6(8), pages 1-21, August.
- Chih-Chien Wang & Chih-Yun Huang & Meng-Chang Lee & Dung-Jang Tsai & Chia-Chun Wu & Sui-Lung Su, 2021. "Genetic association between TNF-α G-308A and osteoarthritis in Asians: A case–control study and meta-analysis," PLOS ONE, Public Library of Science, vol. 16(11), pages 1-15, November.
- Toshiyuki Ko & Seitaro Nomura & Shintaro Yamada & Kanna Fujita & Takanori Fujita & Masahiro Satoh & Chio Oka & Manami Katoh & Masamichi Ito & Mikako Katagiri & Tatsuro Sassa & Bo Zhang & Satoshi Hatsu, 2022. "Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- Huimei Chen & Gabriel Chew & Nithya Devapragash & Jui Zhi Loh & Kevin Y. Huang & Jing Guo & Shiyang Liu & Elisabeth Li Sa Tan & Shuang Chen & Nicole Gui Zhen Tee & Masum M. Mia & Manvendra K. Singh & , 2022. "The E3 ubiquitin ligase WWP2 regulates pro-fibrogenic monocyte infiltration and activity in heart fibrosis," Nature Communications, Nature, vol. 13(1), pages 1-21, December.
- Luca Marchetti & Rosario Lombardo & Corrado Priami, 2017. "HSimulator: Hybrid Stochastic/Deterministic Simulation of Biochemical Reaction Networks," Complexity, Hindawi, vol. 2017, pages 1-12, December.
- Yuma Horii & Shoichi Matsuda & Chikashi Toyota & Takumi Morinaga & Takeo Nakaya & Soken Tsuchiya & Masaki Ohmuraya & Takanori Hironaka & Ryo Yoshiki & Kotaro Kasai & Yuto Yamauchi & Noburo Takizawa & , 2023. "VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid–liquid phase separation," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
- Mingming Zhao & Haoran Wei & Chenze Li & Rui Zhan & Changjie Liu & Jianing Gao & Yaodong Yi & Xiao Cui & Wenxin Shan & Liang Ji & Bing Pan & Si Cheng & Moshi Song & Haipeng Sun & Huidi Jiang & Jun Cai, 2022. "Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
- Jason W Locasale & Arup K Chakraborty, 2008. "Regulation of Signal Duration and the Statistical Dynamics of Kinase Activation by Scaffold Proteins," PLOS Computational Biology, Public Library of Science, vol. 4(6), pages 1-12, June.
- Yena Oh & Rimshah Abid & Saif Dababneh & Marwan Bakr & Termeh Aslani & David P. Cook & Barbara C. Vanderhyden & Jin G. Park & Nikhil V. Munshi & Chi-Chung Hui & Kyoung-Han Kim, 2024. "Transcriptional regulation of the postnatal cardiac conduction system heterogeneity," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
- Lina Chen & Wan Li & Liangcai Zhang & Hong Wang & Weiming He & Jingxie Tai & Xu Li & Xia Li, 2011. "Disease Gene Interaction Pathways: A Potential Framework for How Disease Genes Associate by Disease-Risk Modules," PLOS ONE, Public Library of Science, vol. 6(9), pages 1-12, September.
- Sara Ranjbarvaziri & Aliya Zeng & Iris Wu & Amara Greer-Short & Farshad Farshidfar & Ana Budan & Emma Xu & Reva Shenwai & Matthew Kozubov & Cindy Li & Melissa Van Pell & Francis Grafton & Charles E Ma, 2024. "Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-52068-0. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through the various RePEc services.