IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v15y2024i1d10.1038_s41467-024-50106-5.html
   My bibliography  Save this article

Natural variation of TBR confers plant zinc toxicity tolerance through root cell wall pectin methylesterification

Author

Listed:
  • Kaizhen Zhong

    (China National Rice Research Institute
    Salk Institute for Biological Studies
    Jiangxi Agricultural University)

  • Peng Zhang

    (China National Rice Research Institute)

  • Xiangjin Wei

    (China National Rice Research Institute)

  • Matthieu Pierre Platre

    (Salk Institute for Biological Studies)

  • Wenrong He

    (Salk Institute for Biological Studies)

  • Ling Zhang

    (Salk Institute for Biological Studies)

  • Anna Małolepszy

    (Salk Institute for Biological Studies)

  • Min Cao

    (Salk Institute for Biological Studies)

  • Shikai Hu

    (China National Rice Research Institute)

  • Shaoqing Tang

    (China National Rice Research Institute)

  • Baohai Li

    (Salk Institute for Biological Studies
    Zhejiang University)

  • Peisong Hu

    (China National Rice Research Institute
    Jiangxi Agricultural University)

  • Wolfgang Busch

    (Salk Institute for Biological Studies)

Abstract

Zinc (Zn) is an essential micronutrient but can be cytotoxic when present in excess. Plants have evolved mechanisms to tolerate Zn toxicity. To identify genetic loci responsible for natural variation of plant tolerance to Zn toxicity, we conduct genome-wide association studies for root growth responses to high Zn and identify 21 significant associated loci. Among these loci, we identify Trichome Birefringence (TBR) allelic variation determining root growth variation in high Zn conditions. Natural alleles of TBR determine TBR transcript and protein levels which affect pectin methylesterification in root cell walls. Together with previously published data showing that pectin methylesterification increase goes along with decreased Zn binding to cell walls in TBR mutants, our findings lead to a model in which TBR allelic variation enables Zn tolerance through modulating root cell wall pectin methylesterification. The role of TBR in Zn tolerance is conserved across dicot and monocot plant species.

Suggested Citation

  • Kaizhen Zhong & Peng Zhang & Xiangjin Wei & Matthieu Pierre Platre & Wenrong He & Ling Zhang & Anna Małolepszy & Min Cao & Shikai Hu & Shaoqing Tang & Baohai Li & Peisong Hu & Wolfgang Busch, 2024. "Natural variation of TBR confers plant zinc toxicity tolerance through root cell wall pectin methylesterification," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-50106-5
    DOI: 10.1038/s41467-024-50106-5
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-024-50106-5
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-024-50106-5?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Marc Hanikenne & Ina N. Talke & Michael J. Haydon & Christa Lanz & Andrea Nolte & Patrick Motte & Juergen Kroymann & Detlef Weigel & Ute Krämer, 2008. "Evolution of metal hyperaccumulation required cis-regulatory changes and triplication of HMA4," Nature, Nature, vol. 453(7193), pages 391-395, May.
    2. Baohai Li & Li Sun & Jianyan Huang & Christian Göschl & Weiming Shi & Joanne Chory & Wolfgang Busch, 2019. "GSNOR provides plant tolerance to iron toxicity via preventing iron-dependent nitrosative and oxidative cytotoxicity," Nature Communications, Nature, vol. 10(1), pages 1-13, December.
    3. Debbie Winter & Ben Vinegar & Hardeep Nahal & Ron Ammar & Greg V Wilson & Nicholas J Provart, 2007. "An “Electronic Fluorescent Pictograph” Browser for Exploring and Analyzing Large-Scale Biological Data Sets," PLOS ONE, Public Library of Science, vol. 2(8), pages 1-12, August.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Matthieu Pierre Platre & Santosh B. Satbhai & Lukas Brent & Matias F. Gleason & Min Cao & Magali Grison & Marie Glavier & Ling Zhang & Christophe Gaillochet & Christian Goeschl & Marco Giovannetti & B, 2022. "The receptor kinase SRF3 coordinates iron-level and flagellin dependent defense and growth responses in plants," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    2. Sarah Guiziou & Cassandra J. Maranas & Jonah C. Chu & Jennifer L. Nemhauser, 2023. "An integrase toolbox to record gene-expression during plant development," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    3. Zenglin Li & David J. Sheerin & Edda Roepenack-Lahaye & Mark Stahl & Andreas Hiltbrunner, 2022. "The phytochrome interacting proteins ERF55 and ERF58 repress light-induced seed germination in Arabidopsis thaliana," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    4. Otto, Moritz & Wiehe, Thomas, 2023. "The structured coalescent in the context of gene copy number variation," Theoretical Population Biology, Elsevier, vol. 154(C), pages 67-78.
    5. Ricardo F. H. Giehl & Paulina Flis & Jörg Fuchs & Yiqun Gao & David E. Salt & Nicolaus Wirén, 2023. "Cell type-specific mapping of ion distribution in Arabidopsis thaliana roots," Nature Communications, Nature, vol. 14(1), pages 1-12, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-50106-5. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.