Stabilization of pre-existing neurotensin receptor conformational states by β-arrestin-1 and the biased allosteric modulator ML314
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DOI: 10.1038/s41467-023-38894-8
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- Weijiao Huang & Matthieu Masureel & Qianhui Qu & John Janetzko & Asuka Inoue & Hideaki E. Kato & Michael J. Robertson & Khanh C. Nguyen & Jeffrey S. Glenn & Georgios Skiniotis & Brian K. Kobilka, 2020. "Structure of the neurotensin receptor 1 in complex with β-arrestin 1," Nature, Nature, vol. 579(7798), pages 303-308, March.
- Kathryn M. Hart & Chris M. W. Ho & Supratik Dutta & Michael L. Gross & Gregory R. Bowman, 2016. "Modelling proteins’ hidden conformations to predict antibiotic resistance," Nature Communications, Nature, vol. 7(1), pages 1-10, December.
- Jun Xu & Qinggong Wang & Harald Hübner & Yunfei Hu & Xiaogang Niu & Haoqing Wang & Shoji Maeda & Asuka Inoue & Yuyong Tao & Peter Gmeiner & Yang Du & Changwen Jin & Brian K. Kobilka, 2023. "Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
- F. Pontiggia & D.V. Pachov & M.W. Clarkson & J. Villali & M.F. Hagan & V.S. Pande & D. Kern, 2015. "Free energy landscape of activation in a signalling protein at atomic resolution," Nature Communications, Nature, vol. 6(1), pages 1-14, November.
- Marjorie Damian & Maxime Louet & Antoniel Augusto Severo Gomes & Céline M’Kadmi & Séverine Denoyelle & Sonia Cantel & Sophie Mary & Paulo M. Bisch & Jean-Alain Fehrentz & Laurent J. Catoire & Nicolas , 2021. "Allosteric modulation of ghrelin receptor signaling by lipids," Nature Communications, Nature, vol. 12(1), pages 1-15, December.
- Hsin-Yung Yen & Kin Kuan Hoi & Idlir Liko & George Hedger & Michael R. Horrell & Wanling Song & Di Wu & Philipp Heine & Tony Warne & Yang Lee & Byron Carpenter & Andreas Plückthun & Christopher G. Tat, 2018. "PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling," Nature, Nature, vol. 559(7714), pages 423-427, July.
- Yutaro Shiraishi & Mei Natsume & Yutaka Kofuku & Shunsuke Imai & Kunio Nakata & Toshimi Mizukoshi & Takumi Ueda & Hideo Iwaï & Ichio Shimada, 2018. "Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR," Nature Communications, Nature, vol. 9(1), pages 1-10, December.
- Yutaro Shiraishi & Yutaka Kofuku & Takumi Ueda & Shubhi Pandey & Hemlata Dwivedi-Agnihotri & Arun K. Shukla & Ichio Shimada, 2021. "Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR," Nature Communications, Nature, vol. 12(1), pages 1-11, December.
- Hideaki E. Kato & Yan Zhang & Hongli Hu & Carl-Mikael Suomivuori & Francois Marie Ngako Kadji & Junken Aoki & Kaavya Krishna Kumar & Rasmus Fonseca & Daniel Hilger & Weijiao Huang & Naomi R. Latorraca, 2019. "Conformational transitions of a neurotensin receptor 1–Gi1 complex," Nature, Nature, vol. 572(7767), pages 80-85, August.
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