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Associations of timing of physical activity with all-cause and cause-specific mortality in a prospective cohort study

Author

Listed:
  • Hongliang Feng

    (Guangdong Academy of Medical Sciences
    The Chinese University of Hong Kong)

  • Lulu Yang

    (Guangdong Academy of Medical Sciences)

  • Yannis Yan Liang

    (Guangdong Academy of Medical Sciences)

  • Sizhi Ai

    (The Affiliated Brain Hospital of Guangzhou Medical University
    Heart Center, The First Affiliated Hospital of Xinxiang Medical University
    The Chinese University of Hong Kong)

  • Yaping Liu

    (The Chinese University of Hong Kong
    The Chinese University of Hong Kong)

  • Yue Liu

    (Guangdong Academy of Medical Sciences)

  • Xinyi Jin

    (Guangdong Academy of Medical Sciences)

  • Binbin Lei

    (Guangdong Academy of Medical Sciences)

  • Jing Wang

    (The Affiliated Brain Hospital of Guangzhou Medical University
    The Chinese University of Hong Kong)

  • Nana Zheng

    (The Affiliated Brain Hospital of Guangzhou Medical University)

  • Xinru Chen

    (Guangdong Academy of Medical Sciences
    The Affiliated Brain Hospital of Guangzhou Medical University)

  • Joey W. Y. Chan

    (The Chinese University of Hong Kong
    The Chinese University of Hong Kong)

  • Raymond Kim Wai Sum

    (The Chinese University of Hong Kong)

  • Ngan Yin Chan

    (The Chinese University of Hong Kong
    The Chinese University of Hong Kong)

  • Xiao Tan

    (Zhejiang University School of Public Health and Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
    Uppsala University)

  • Christian Benedict

    (Uppsala University)

  • Yun Kwok Wing

    (The Chinese University of Hong Kong
    The Chinese University of Hong Kong)

  • Jihui Zhang

    (The Affiliated Brain Hospital of Guangzhou Medical University
    The Chinese University of Hong Kong
    Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University
    Guangzhou Medical University)

Abstract

There is a growing interest in the role of timing of daily behaviors in improving health. However, little is known about the optimal timing of physical activity to maximize health benefits. We perform a cohort study of 92,139 UK Biobank participants with valid accelerometer data and all-cause and cause-specific mortality outcomes, comprising over 7 years of median follow-up (638,825 person-years). Moderate-to-vigorous intensity physical activity (MVPA) at any time of day is associated with lower risks for all-cause, cardiovascular disease, and cancer mortality. In addition, compared with morning group (>50% of daily MVPA during 05:00-11:00), midday-afternoon (11:00-17:00) and mixed MVPA timing groups, but not evening group (17:00-24:00), have lower risks of all-cause and cardiovascular disease mortality. These protective associations are more pronounced among the elderly, males, less physically active participants, or those with preexisting cardiovascular diseases. Here, we show that MVPA timing may have the potential to improve public health.

Suggested Citation

  • Hongliang Feng & Lulu Yang & Yannis Yan Liang & Sizhi Ai & Yaping Liu & Yue Liu & Xinyi Jin & Binbin Lei & Jing Wang & Nana Zheng & Xinru Chen & Joey W. Y. Chan & Raymond Kim Wai Sum & Ngan Yin Chan &, 2023. "Associations of timing of physical activity with all-cause and cause-specific mortality in a prospective cohort study," Nature Communications, Nature, vol. 14(1), pages 1-10, December.
    • Handle: RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-36546-5
    DOI: 10.1038/s41467-023-36546-5
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