Identification of a binding site on soluble RANKL that can be targeted to inhibit soluble RANK-RANKL interactions and treat osteoporosis
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DOI: 10.1038/s41467-022-33006-4
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- Yuki Ikebuchi & Shigeki Aoki & Masashi Honma & Madoka Hayashi & Yasutaka Sugamori & Masud Khan & Yoshiaki Kariya & Genki Kato & Yasuhiko Tabata & Josef M. Penninger & Nobuyuki Udagawa & Kazuhiro Aoki , 2018. "Coupling of bone resorption and formation by RANKL reverse signalling," Nature, Nature, vol. 561(7722), pages 195-200, September.
- D. Holstead Jones & Tomoki Nakashima & Otto H. Sanchez & Ivona Kozieradzki & Svetlana V. Komarova & Ildiko Sarosi & Sean Morony & Evelyn Rubin & Renu Sarao & Carlo V. Hojilla & Vukoslav Komnenovic & Y, 2006. "Regulation of cancer cell migration and bone metastasis by RANKL," Nature, Nature, vol. 440(7084), pages 692-696, March.
- Jinhu Xiong & Keisha Cawley & Marilina Piemontese & Yuko Fujiwara & Haibo Zhao & Joseph J. Goellner & Charles A. O’Brien, 2018. "Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss," Nature Communications, Nature, vol. 9(1), pages 1-7, December.
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