Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis
Author
Abstract
Suggested Citation
DOI: 10.1038/s41467-022-32789-w
Download full text from publisher
References listed on IDEAS
- Emily E. Wrenbeck & Laura R. Azouz & Timothy A. Whitehead, 2017. "Single-mutation fitness landscapes for an enzyme on multiple substrates reveal specificity is globally encoded," Nature Communications, Nature, vol. 8(1), pages 1-10, August.
- Corin C. Wagen & Spencer E. McMinn & Eugene E. Kwan & Eric N. Jacobsen, 2022. "Screening for generality in asymmetric catalysis," Nature, Nature, vol. 610(7933), pages 680-686, October.
- Linfeng Xu & Kai-Chun Chang & Emory M. Payne & Cyrus Modavi & Leqian Liu & Claire M. Palmer & Nannan Tao & Hal S. Alper & Robert T. Kennedy & Dale S. Cornett & Adam R. Abate, 2021. "Mapping enzyme catalysis with metabolic biosensing," Nature Communications, Nature, vol. 12(1), pages 1-7, December.
- Fuqiang Ma & Meng Ting Chung & Yuan Yao & Robert Nidetz & Lap Man Lee & Allen P. Liu & Yan Feng & Katsuo Kurabayashi & Guang-Yu Yang, 2018. "Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic droplet screening platform," Nature Communications, Nature, vol. 9(1), pages 1-8, December.
- Edward Kalkreuter & Kyle S. Bingham & Aaron M. Keeler & Andrew N. Lowell & Jennifer J. Schmidt & David H. Sherman & Gavin J. Williams, 2021. "Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase," Nature Communications, Nature, vol. 12(1), pages 1-12, December.
Most related items
These are the items that most often cite the same works as this one and are cited by the same works as this one.- Guifa Zhai & Yan Zhu & Guo Sun & Fan Zhou & Yangning Sun & Zhou Hong & Chuan Dong & Peter F. Leadlay & Kui Hong & Zixin Deng & Fuling Zhou & Yuhui Sun, 2023. "Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition," Nature Communications, Nature, vol. 14(1), pages 1-12, December.
- Rosario Vanella & Christoph Küng & Alexandre A. Schoepfer & Vanni Doffini & Jin Ren & Michael A. Nash, 2024. "Understanding activity-stability tradeoffs in biocatalysts by enzyme proximity sequencing," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
- Wenjing Nie & Qiongqiong Wan & Jian Sun & Moran Chen & Ming Gao & Suming Chen, 2023. "Ultra-high-throughput mapping of the chemical space of asymmetric catalysis enables accelerated reaction discovery," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
- Ahreum Kim & Chanhee Lee & Jayoung Song & Sang Kook Lee & Yongseok Kwon, 2023. "All-round catalytic and atroposelective strategy via dynamic kinetic resolution for N-/2-/3-arylindoles," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
- Jianhua Wei & Xuan Zhang & Yucong Zhou & Xingnuo Cheng & Zhi Lin & Mancheng Tang & Jianting Zheng & Binju Wang & Qianjin Kang & Linquan Bai, 2022. "Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-32789-w. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through the various RePEc services.