SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization
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DOI: 10.1038/s41467-022-32262-8
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- Yunlong Cao & Jing Wang & Fanchong Jian & Tianhe Xiao & Weiliang Song & Ayijiang Yisimayi & Weijin Huang & Qianqian Li & Peng Wang & Ran An & Jing Wang & Yao Wang & Xiao Niu & Sijie Yang & Hui Liang &, 2022. "Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies," Nature, Nature, vol. 602(7898), pages 657-663, February.
- James W. Saville & Dhiraj Mannar & Xing Zhu & Shanti S. Srivastava & Alison M. Berezuk & Jean-Philippe Demers & Steven Zhou & Katharine S. Tuttle & Inna Sekirov & Andrew Kim & Wei Li & Dimiter S. Dimi, 2022. "Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
- Dora Pinto & Young-Jun Park & Martina Beltramello & Alexandra C. Walls & M. Alejandra Tortorici & Siro Bianchi & Stefano Jaconi & Katja Culap & Fabrizia Zatta & Anna De Marco & Alessia Peter & Barbara, 2020. "Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody," Nature, Nature, vol. 583(7815), pages 290-295, July.
- Lihong Liu & Pengfei Wang & Manoj S. Nair & Jian Yu & Micah Rapp & Qian Wang & Yang Luo & Jasper F.-W. Chan & Vincent Sahi & Amir Figueroa & Xinzheng V. Guo & Gabriele Cerutti & Jude Bimela & Jason Go, 2020. "Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike," Nature, Nature, vol. 584(7821), pages 450-456, August.
- Jiandong Huo & Halina Mikolajek & Audrey Bas & Jordan J. Clark & Parul Sharma & Anja Kipar & Joshua Dormon & Chelsea Norman & Miriam Weckener & Daniel K. Clare & Peter J. Harrison & Julia A. Tree & Ka, 2021. "A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19," Nature Communications, Nature, vol. 12(1), pages 1-18, December.
- Christopher O. Barnes & Claudia A. Jette & Morgan E. Abernathy & Kim-Marie A. Dam & Shannon R. Esswein & Harry B. Gristick & Andrey G. Malyutin & Naima G. Sharaf & Kathryn E. Huey-Tubman & Yu E. Lee &, 2020. "SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies," Nature, Nature, vol. 588(7839), pages 682-687, December.
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- Hu Li & Huarui Gong & Tsz Hung Wong & Jingkun Zhou & Yuqiong Wang & Long Lin & Ying Dou & Huiling Jia & Xingcan Huang & Zhan Gao & Rui Shi & Ya Huang & Zhenlin Chen & Wooyoung PARK & Ji Yu Li & Hongwe, 2023. "Wireless, battery-free, multifunctional integrated bioelectronics for respiratory pathogens monitoring and severity evaluation," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
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