Biallelic and gene-wide genomic substitution for endogenous intron and retroelement mutagenesis in human cells
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DOI: 10.1038/s41467-022-31982-1
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- Matthew C. Canver & Elenoe C. Smith & Falak Sher & Luca Pinello & Neville E. Sanjana & Ophir Shalem & Diane D. Chen & Patrick G. Schupp & Divya S. Vinjamur & Sara P. Garcia & Sidinh Luc & Ryo Kurita &, 2015. "BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis," Nature, Nature, vol. 527(7577), pages 192-197, November.
- Julie Parenteau & Laurine Maignon & Mélodie Berthoumieux & Mathieu Catala & Vanessa Gagnon & Sherif Abou Elela, 2019. "Introns are mediators of cell response to starvation," Nature, Nature, vol. 565(7741), pages 612-617, January.
- Gill Bejerano & Craig B. Lowe & Nadav Ahituv & Bryan King & Adam Siepel & Sofie R. Salama & Edward M. Rubin & W. James Kent & David Haussler, 2006. "A distal enhancer and an ultraconserved exon are derived from a novel retroposon," Nature, Nature, vol. 441(7089), pages 87-90, May.
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