Integrating 3D genomic and epigenomic data to enhance target gene discovery and drug repurposing in transcriptome-wide association studies
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DOI: 10.1038/s41467-022-30956-7
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- Xiaoguang Xu & Chachrit Khunsriraksakul & James M. Eales & Sebastien Rubin & David Scannali & Sushant Saluja & David Talavera & Havell Markus & Lida Wang & Maciej Drzal & Akhlaq Maan & Abigail C. Lay , 2024. "Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets," Nature Communications, Nature, vol. 15(1), pages 1-29, December.
- Chachrit Khunsriraksakul & Qinmengge Li & Havell Markus & Matthew T. Patrick & Renan Sauteraud & Daniel McGuire & Xingyan Wang & Chen Wang & Lida Wang & Siyuan Chen & Ganesh Shenoy & Bingshan Li & Xue, 2023. "Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
- Lida Wang & Chachrit Khunsriraksakul & Havell Markus & Dieyi Chen & Fan Zhang & Fang Chen & Xiaowei Zhan & Laura Carrel & Dajiang. J. Liu & Bibo Jiang, 2024. "Integrating single cell expression quantitative trait loci summary statistics to understand complex trait risk genes," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
- Ying Chang & Yao Zhou & Junrui Zhou & Wen Li & Jiasong Cao & Yaqing Jing & Shan Zhang & Yongmei Shen & Qimei Lin & Xutong Fan & Hongxi Yang & Xiaobao Dong & Shijie Zhang & Xianfu Yi & Ling Shuai & Lei, 2023. "Unraveling the causal genes and transcriptomic determinants of human telomere length," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
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