CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids
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DOI: 10.1038/s41467-022-30186-x
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- Kimberly L. Cooper & Karen E. Sears & Aysu Uygur & Jennifer Maier & Karl-Stephan Baczkowski & Margaret Brosnahan & Doug Antczak & Julian A. Skidmore & Clifford J. Tabin, 2014. "Patterning and post-patterning modes of evolutionary digit loss in mammals," Nature, Nature, vol. 511(7507), pages 41-45, July.
- Xiaofeng Qi & Heng Liu & Bonne Thompson & Jeffrey McDonald & Cheng Zhang & Xiaochun Li, 2019. "Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi," Nature, Nature, vol. 571(7764), pages 279-283, July.
- Xiaofeng Qi & Philip Schmiege & Elias Coutavas & Jiawei Wang & Xiaochun Li, 2018. "Structures of human Patched and its complex with native palmitoylated sonic hedgehog," Nature, Nature, vol. 560(7716), pages 128-132, August.
- Ishan Deshpande & Jiahao Liang & Danielle Hedeen & Kelsey J. Roberts & Yunxiao Zhang & Betty Ha & Naomi R. Latorraca & Bryan Faust & Ron O. Dror & Philip A. Beachy & Benjamin R. Myers & Aashish Mangli, 2019. "Smoothened stimulation by membrane sterols drives Hedgehog pathway activity," Nature, Nature, vol. 571(7764), pages 284-288, July.
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