Integrating gene expression and clinical data to identify drug repurposing candidates for hyperlipidemia and hypertension
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DOI: 10.1038/s41467-021-27751-1
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- Dorothée Diogo & Chao Tian & Christopher S. Franklin & Mervi Alanne-Kinnunen & Michael March & Chris C. A. Spencer & Ciara Vangjeli & Michael E. Weale & Hannele Mattsson & Elina Kilpeläinen & Patrick , 2018. "Phenome-wide association studies across large population cohorts support drug target validation," Nature Communications, Nature, vol. 9(1), pages 1-13, December.
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- Xiaoguang Xu & Chachrit Khunsriraksakul & James M. Eales & Sebastien Rubin & David Scannali & Sushant Saluja & David Talavera & Havell Markus & Lida Wang & Maciej Drzal & Akhlaq Maan & Abigail C. Lay , 2024. "Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets," Nature Communications, Nature, vol. 15(1), pages 1-29, December.
- Marcin Pilarczyk & Mehdi Fazel-Najafabadi & Michal Kouril & Behrouz Shamsaei & Juozas Vasiliauskas & Wen Niu & Naim Mahi & Lixia Zhang & Nicholas A. Clark & Yan Ren & Shana White & Rashid Karim & Huan, 2022. "Connecting omics signatures and revealing biological mechanisms with iLINCS," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
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