The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression
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DOI: 10.1038/s41467-021-27539-3
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- Isaia Barbieri & Konstantinos Tzelepis & Luca Pandolfini & Junwei Shi & Gonzalo Millán-Zambrano & Samuel C. Robson & Demetrios Aspris & Valentina Migliori & Andrew J. Bannister & Namshik Han & Etienne, 2017. "Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control," Nature, Nature, vol. 552(7683), pages 126-131, December.
- Junho Choe & Shuibin Lin & Wencai Zhang & Qi Liu & Longfei Wang & Julia Ramirez-Moya & Peng Du & Wantae Kim & Shaojun Tang & Piotr Sliz & Pilar Santisteban & Rani E. George & William G. Richards & Kwo, 2018. "mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis," Nature, Nature, vol. 561(7724), pages 556-560, September.
- Yuqin Wang & Ming Gao & Fuxing Zhu & Xinzhi Li & Ying Yang & Qiuxin Yan & Linna Jia & Liwei Xie & Zheng Chen, 2020. "METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice," Nature Communications, Nature, vol. 11(1), pages 1-14, December.
- Wenqi Xu & Jiahui Li & Chenxi He & Jing Wen & Honghui Ma & Bowen Rong & Jianbo Diao & Liyong Wang & Jiahua Wang & Feizhen Wu & Li Tan & Yujiang Geno Shi & Yang Shi & Hongjie Shen, 2021. "METTL3 regulates heterochromatin in mouse embryonic stem cells," Nature, Nature, vol. 591(7849), pages 317-321, March.
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- Xinzhi Li & Kaixin Ding & Xueying Li & Bingchuan Yuan & Yuqin Wang & Zhicheng Yao & Shuaikang Wang & He Huang & Bolin Xu & Liwei Xie & Tuo Deng & Xiao-wei Chen & Zheng Chen, 2022. "Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH)," Nature Communications, Nature, vol. 13(1), pages 1-19, December.
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