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The barley immune receptor Mla recognizes multiple pathogens and contributes to host range dynamics

Author

Listed:
  • Jan Bettgenhaeuser

    (University of East Anglia
    KWS SAAT SE & Co. KGaA)

  • Inmaculada Hernández-Pinzón

    (University of East Anglia)

  • Andrew M. Dawson

    (University of East Anglia)

  • Matthew Gardiner

    (University of East Anglia)

  • Phon Green

    (University of East Anglia)

  • Jodie Taylor

    (University of East Anglia)

  • Matthew Smoker

    (University of East Anglia)

  • John N. Ferguson

    (University of East Anglia
    University of Cambridge)

  • Peter Emmrich

    (University of East Anglia
    John Innes Centre)

  • Amelia Hubbard

    (NIAB)

  • Rosemary Bayles

    (NIAB)

  • Robbie Waugh

    (The James Hutton Institute, Invergowrie)

  • Brian J. Steffenson

    (University of Minnesota)

  • Brande B. H. Wulff

    (University of East Anglia
    King Abdullah University of Science and Technology)

  • Antonín Dreiseitl

    (Agrotest Fyto Ltd)

  • Eric R. Ward

    (University of East Anglia
    AgBiome)

  • Matthew J. Moscou

    (University of East Anglia)

Abstract

Crop losses caused by plant pathogens are a primary threat to stable food production. Stripe rust (Puccinia striiformis) is a fungal pathogen of cereal crops that causes significant, persistent yield loss. Stripe rust exhibits host species specificity, with lineages that have adapted to infect wheat and barley. While wheat stripe rust and barley stripe rust are commonly restricted to their corresponding hosts, the genes underlying this host specificity remain unknown. Here, we show that three resistance genes, Rps6, Rps7, and Rps8, contribute to immunity in barley to wheat stripe rust. Rps7 cosegregates with barley powdery mildew resistance at the Mla locus. Using transgenic complementation of different Mla alleles, we confirm allele-specific recognition of wheat stripe rust by Mla. Our results show that major resistance genes contribute to the host species specificity of wheat stripe rust on barley and that a shared genetic architecture underlies resistance to the adapted pathogen barley powdery mildew and non-adapted pathogen wheat stripe rust.

Suggested Citation

  • Jan Bettgenhaeuser & Inmaculada Hernández-Pinzón & Andrew M. Dawson & Matthew Gardiner & Phon Green & Jodie Taylor & Matthew Smoker & John N. Ferguson & Peter Emmrich & Amelia Hubbard & Rosemary Bay, 2021. "The barley immune receptor Mla recognizes multiple pathogens and contributes to host range dynamics," Nature Communications, Nature, vol. 12(1), pages 1-14, December.
    • Handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-27288-3
    DOI: 10.1038/s41467-021-27288-3
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    References listed on IDEAS

    as
    1. Jonathan D. G. Jones & Jeffery L. Dangl, 2006. "The plant immune system," Nature, Nature, vol. 444(7117), pages 323-329, November.
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