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Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer

Author

Listed:
  • Maximilian W. Schenk

    (University of Manchester)

  • Sam Humphrey

    (University of Manchester)

  • A. S. Md Mukarram Hossain

    (University of Manchester)

  • Mitchell Revill

    (University of Manchester)

  • Sarah Pearsall

    (University of Manchester)

  • Alice Lallo

    (University of Manchester)

  • Stewart Brown

    (University of Manchester)

  • Samuel Bratt

    (University of Manchester)

  • Melanie Galvin

    (University of Manchester)

  • Tine Descamps

    (University of Manchester)

  • Cong Zhou

    (University of Manchester)

  • Simon P. Pearce

    (University of Manchester)

  • Lynsey Priest

    (University of Manchester)

  • Michelle Greenhalgh

    (The University of Manchester)

  • Anshuman Chaturvedi

    (The University of Manchester)

  • Alastair Kerr

    (University of Manchester
    Cancer Research UK Lung Cancer Centre of Excellence at the University of Manchester)

  • Fiona Blackhall

    (The University of Manchester
    Cancer Research UK Lung Cancer Centre of Excellence at the University of Manchester
    University of Manchester)

  • Caroline Dive

    (University of Manchester
    Cancer Research UK Lung Cancer Centre of Excellence at the University of Manchester)

  • Kristopher K. Frese

    (University of Manchester
    Cancer Research UK Lung Cancer Centre of Excellence at the University of Manchester)

Abstract

Small cell lung cancer (SCLC) has a 5-year survival rate of

Suggested Citation

  • Maximilian W. Schenk & Sam Humphrey & A. S. Md Mukarram Hossain & Mitchell Revill & Sarah Pearsall & Alice Lallo & Stewart Brown & Samuel Bratt & Melanie Galvin & Tine Descamps & Cong Zhou & Simon P. , 2021. "Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer," Nature Communications, Nature, vol. 12(1), pages 1-15, December.
    • Handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-26823-6
    DOI: 10.1038/s41467-021-26823-6
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    References listed on IDEAS

    as
    1. Jing Shan Lim & Alvaro Ibaseta & Marcus M. Fischer & Belinda Cancilla & Gilbert O’Young & Sandra Cristea & Vincent C. Luca & Dian Yang & Nadine S. Jahchan & Cécile Hamard & Martine Antoine & Marie Wis, 2017. "Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer," Nature, Nature, vol. 545(7654), pages 360-364, May.
    2. Yunlu Kang & Rui Liu & Jing-Xiang Wu & Lei Chen, 2019. "Structural insights into the mechanism of human soluble guanylate cyclase," Nature, Nature, vol. 574(7777), pages 206-210, October.
    3. Stuart C. Williamson & Robert L. Metcalf & Francesca Trapani & Sumitra Mohan & Jenny Antonello & Benjamin Abbott & Hui Sun Leong & Christopher P. E. Chester & Nicole Simms & Radoslaw Polanski & Daisuk, 2016. "Vasculogenic mimicry in small cell lung cancer," Nature Communications, Nature, vol. 7(1), pages 1-14, December.
    4. Alex H. Wagner & Siddhartha Devarakonda & Zachary L. Skidmore & Kilannin Krysiak & Avinash Ramu & Lee Trani & Jason Kunisaki & Ashiq Masood & Saiama N. Waqar & Nicholas C. Spies & Daniel Morgensztern , 2018. "Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer," Nature Communications, Nature, vol. 9(1), pages 1-11, December.
    Full references (including those not matched with items on IDEAS)

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