Low-dose decitabine priming endows CAR T cells with enhanced and persistent antitumour potential via epigenetic reprogramming
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DOI: 10.1038/s41467-020-20696-x
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Cited by:
- Bihui Cao & Manting Liu & Lu Wang & Kangshun Zhu & Mingyue Cai & Xiaopei Chen & Yunfei Feng & Shuo Yang & Shengyu Fu & Cheng Zhi & Xiaodie Ye & Jian Zhang & Zhiru Zhang & Xin Yang & Ming Zhao & Qingde, 2022. "Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
- Vipul Bhatia & Nikhil V. Kamat & Tiffany E. Pariva & Li-Ting Wu & Annabelle Tsao & Koichi Sasaki & Huiyun Sun & Gerardo Javier & Sam Nutt & Ilsa Coleman & Lauren Hitchcock & Ailin Zhang & Dmytro Rudoy, 2023. "Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy," Nature Communications, Nature, vol. 14(1), pages 1-23, December.
- Fengqi Qiu & Peishan Jiang & Guiheng Zhang & Jie An & Kexin Ruan & Xiaowen Lyu & Jianya Zhou & Wanqiang Sheng, 2024. "Priming with LSD1 inhibitors promotes the persistence and antitumor effect of adoptively transferred T cells," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- Maxine S. Y. Lam & Jose Antonio Reales-Calderon & Jin Rong Ow & Joey J. Y. Aw & Damien Tan & Ragavi Vijayakumar & Erica Ceccarello & Tommaso Tabaglio & Yan Ting Lim & Wang Loo Chien & Fritz Lai & Anth, 2023. "G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
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