Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy
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Abstract
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DOI: 10.1038/s41467-020-20223-y
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Cited by:
- Ziwei Dai & Weiyan Zheng & Jason W. Locasale, 2022. "Amino acid variability, tradeoffs and optimality in human diet," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
- Gabrielle Manteaux & Alix Amsel & Blanche Riquier-Morcant & Jaime Prieto Romero & Laurie Gayte & Benjamin Fourneaux & Marion Larroque & Nadège Gruel & Chloé Quignot & Gaelle Perot & Solenn Jacq & Madi, 2024. "A metabolic crosstalk between liposarcoma and muscle sustains tumor growth," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
- Nicole Kiweler & Catherine Delbrouck & Vitaly I. Pozdeev & Laura Neises & Leticia Soriano-Baguet & Kim Eiden & Feng Xian & Mohaned Benzarti & Lara Haase & Eric Koncina & Maryse Schmoetten & Christian , 2022. "Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- Li Luo & Xingyun Wu & Jiawu Fan & Lixia Dong & Mao Wang & Yan Zeng & Sijia Li & Wenyong Yang & Jingwen Jiang & Kui Wang, 2024. "FBXO7 ubiquitinates PRMT1 to suppress serine synthesis and tumor growth in hepatocellular carcinoma," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
- Kui Wang & Li Luo & Shuyue Fu & Mao Wang & Zihao Wang & Lixia Dong & Xingyun Wu & Lunzhi Dai & Yong Peng & Guobo Shen & Hai-Ning Chen & Edouard Collins Nice & Xiawei Wei & Canhua Huang, 2023. "PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinoma," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
- Camilla Tombari & Alessandro Zannini & Rebecca Bertolio & Silvia Pedretti & Matteo Audano & Luca Triboli & Valeria Cancila & Davide Vacca & Manuel Caputo & Sara Donzelli & Ilenia Segatto & Simone Vodr, 2023. "Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth," Nature Communications, Nature, vol. 14(1), pages 1-21, December.
- Marc Hennequart & Christiaan F. Labuschagne & Mylène Tajan & Steven E. Pilley & Eric C. Cheung & Nathalie M. Legrave & Paul C. Driscoll & Karen H. Vousden, 2021. "The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells," Nature Communications, Nature, vol. 12(1), pages 1-10, December.
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