IDEAS home Printed from https://ideas.repec.org/a/kap/jtecht/v39y2014i4p503-523.html
   My bibliography  Save this article

Accelerating commercialization: a new model of strategic foundation funding

Author

Listed:
  • Maryann Feldman
  • Alexandra Graddy-Reed

Abstract

Venture philanthropy presents a new model of research funding that is particularly helpful to those fighting orphan diseases, which actively manages the commercialization process to accelerate scientific progress and material outcomes. This paper begins by documenting the growing importance of foundations as a source of funding academic research as traditional funding from industry and government sources decline. Foundations are known for their innovative techniques and we consider the evolution of the ways that foundations fund academic research and form partnerships across academia and industry. We examine the example of the Cystic Fibrosis Foundation and the development of the drug Kalydeco ® as a demonstration of the principals of strategic foundation funding. The Cystic Fibrosis Foundation adapted to a venture philanthropy model and took an active role in drug development, stewarding the commercialization process from funding basic scientific work in academic institutions, to making an equity investment in a start-up firm. We conclude by evaluating the advantages and disadvantages to venture philanthropy for the academic researchers, industry partners, foundations, and universities and consider an agenda for future research. Copyright Springer Science+Business Media New York 2014

Suggested Citation

  • Maryann Feldman & Alexandra Graddy-Reed, 2014. "Accelerating commercialization: a new model of strategic foundation funding," The Journal of Technology Transfer, Springer, vol. 39(4), pages 503-523, August.
    • Handle: RePEc:kap:jtecht:v:39:y:2014:i:4:p:503-523
    DOI: 10.1007/s10961-013-9311-1
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.1007/s10961-013-9311-1
    Download Restriction: Access to full text is restricted to subscribers.
    File URL: https://libkey.io/10.1007/s10961-013-9311-1?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Auerswald, Philip E & Branscomb, Lewis M, 2003. "Valleys of Death and Darwinian Seas: Financing the Invention to Innovation Transition in the United States," The Journal of Technology Transfer, Springer, vol. 28(3-4), pages 227-239, August.
    2. Patrick Aebischer, 2012. "The price of charity," Nature, Nature, vol. 481(7381), pages 260-260, January.
    3. Heidi Ledford, 2011. "Charities seek cut of drug royalties," Nature, Nature, vol. 475(7356), pages 275-276, July.
    4. Carayol, Nicolas, 2003. "Objectives, agreements and matching in science-industry collaborations: reassembling the pieces of the puzzle," Research Policy, Elsevier, vol. 32(6), pages 887-908, June.
    5. Hart, David M., 2001. "Antitrust and technological innovation in the US: ideas, institutions, decisions, and impacts, 1890-2000," Research Policy, Elsevier, vol. 30(6), pages 923-936, June.
    6. Heidi Ledford, 2012. "Alternative funding: Sponsor my science," Nature, Nature, vol. 481(7381), pages 254-255, January.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Christopher S. Hayter & Andrew J. Nelson & Stephanie Zayed & Alan C. O’Connor, 2018. "Conceptualizing academic entrepreneurship ecosystems: a review, analysis and extension of the literature," The Journal of Technology Transfer, Springer, vol. 43(4), pages 1039-1082, August.
    2. Graddy-Reed, Alexandra, 2020. "Getting ahead in the race for a cure: How nonprofits are financing biomedical R&D," Research Policy, Elsevier, vol. 49(8).
    3. Andrikopoulos, Andreas, 2020. "Delineating social finance," International Review of Financial Analysis, Elsevier, vol. 70(C).
    4. João R. Faria & Franklin G. Mixon, 2018. "Entrepreneurial Philanthropy and University Creation: An Economic Model," Journal of the Knowledge Economy, Springer;Portland International Center for Management of Engineering and Technology (PICMET), vol. 9(3), pages 1067-1086, September.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Gennaro Strazzullo & William J. Ion & Jillian MacBryde, 2022. "An Investigation of the Translational Asset: A Proposed Classification," Journal of the Knowledge Economy, Springer;Portland International Center for Management of Engineering and Technology (PICMET), vol. 13(4), pages 3123-3149, December.
    2. Daniel Nepelski & Vincent Roy & Annarosa Pesole, 2019. "The organisational and geographic diversity and innovation potential of EU-funded research networks," The Journal of Technology Transfer, Springer, vol. 44(2), pages 359-380, April.
    3. Battaglia, Daniele & Landoni, Paolo & Rizzitelli, Francesco, 2017. "Organizational structures for external growth of University Technology Transfer Offices: An explorative analysis," Technological Forecasting and Social Change, Elsevier, vol. 123(C), pages 45-56.
    4. Rachel Levy & Pascale Roux & Sandrine Wolff, 2009. "An analysis of science–industry collaborative patterns in a large European University," The Journal of Technology Transfer, Springer, vol. 34(1), pages 1-23, February.
    5. Albert Banal-Estañol & Inés Macho-Stadler & David Pérez-Castrillo, 2013. "Endogeneous matching in university-industry collaboration: Theory and empirical evidence from the UK," Economics Working Papers 1379, Department of Economics and Business, Universitat Pompeu Fabra.
    6. Munari, Federico & Sobrero, Maurizio & Toschi, Laura, 2018. "The university as a venture capitalist? Gap funding instruments for technology transfer," Technological Forecasting and Social Change, Elsevier, vol. 127(C), pages 70-84.
    7. Nicolas Carayol, 2006. "La production de brevets par les chercheurs et enseignants-chercheurs.. Le cas de l'université Louis Pasteur," Economie & Prévision, La Documentation Française, vol. 0(4), pages 117-134.
    8. Andrey V. Makarov, 2014. "Comparative Analusis Of Antitrust Policy Against Collusion In Some Transition Economies: Challenges For Effectiveness," HSE Working papers WP BRP 20/PA/2014, National Research University Higher School of Economics.
    9. Munari, Federico & Toschi, Laura, 2021. "The impact of public funding on science valorisation: an analysis of the ERC Proof-of-Concept Programme," Research Policy, Elsevier, vol. 50(6).
    10. Rene Belderbos & Victor Gilsing & Shinya Suzuki, 2015. "Direct and mediated ties to universities: ‘Scientific’ absorptive capacity and innovation performance of pharmaceutical firms," Working Papers of Department of Management, Strategy and Innovation, Leuven 504836, KU Leuven, Faculty of Economics and Business (FEB), Department of Management, Strategy and Innovation, Leuven.
    11. Hoppmann, Joern, 2021. "Hand in hand to Nowhereland? How the resource dependence of research institutes influences their co-evolution with industry," Research Policy, Elsevier, vol. 50(2).
    12. Ajay Bhaskarabhatla & Enrico Pennings, 2012. "Defensive Disclosure under Antitrust Enforcement," Tinbergen Institute Discussion Papers 12-010/2, Tinbergen Institute.
    13. Hameeda A. AlMalki & Christopher M. Durugbo, 2023. "Systematic review of institutional innovation literature: towards a multi-level management model," Management Review Quarterly, Springer, vol. 73(2), pages 731-785, June.
    14. Daniel Nepelski & Maciej Sobolewski, 2020. "Estimating investments in General Purpose Technologies. The case of AI Investments in Europe," JRC Research Reports JRC118953, Joint Research Centre.
    15. Bernd Wurth & Niall G. MacKenzie & Susan Howick, 2024. "Not seeing the forest for the trees? A systems approach to the entrepreneurial university," Small Business Economics, Springer, vol. 63(2), pages 1-24, August.
    16. Dang, Canh Thien & Owens, Trudy, 2020. "Does transparency come at the cost of charitable services? Evidence from investigating British charities," Journal of Economic Behavior & Organization, Elsevier, vol. 172(C), pages 314-343.
    17. Nathalie Duval-Couetil & Michael Ladisch & Soohyun Yi, 2021. "Addressing academic researcher priorities through science and technology entrepreneurship education," The Journal of Technology Transfer, Springer, vol. 46(2), pages 288-318, April.
    18. Razieh Nejabat & Marina Van Geenhuizen, 2019. "Entrepreneurial Risk-Taking in Sustainable Energy: University Spin-Off Firms and Market Introduction in Northwest Europe," Sustainability, MDPI, vol. 11(24), pages 1-23, December.
    19. Cowling, Marc & Fryges, Helmut & Licht, Georg & Murray, Gordon, 2007. "The survival and growth of 'adolescent' high-tech firms in Germany and the UK, 1997-2003," ZEW Expertises, ZEW - Leibniz Centre for European Economic Research, number 110480, March.
    20. Liu, Xing & Wu, Xianhua & Zhang, Weipan, 2024. "A new DEA model and its application in performance evaluation of scientific research activities in the universities of China's double first-class initiative," Socio-Economic Planning Sciences, Elsevier, vol. 92(C).

    More about this item

    Keywords

    Venture philanthropy; Academic research; Drug development; Cystic fibrosis; O32; O33; P43;
    All these keywords.

    JEL classification:

    • O32 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Management of Technological Innovation and R&D
    • O33 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Technological Change: Choices and Consequences; Diffusion Processes
    • P43 - Political Economy and Comparative Economic Systems - - Other Economic Systems - - - Finance; Public Finance

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:kap:jtecht:v:39:y:2014:i:4:p:503-523. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.