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dlmap: An R Package for Mixed Model QTL and Association Analysis

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  • Huang, B. Emma
  • Shah, Rohan
  • George, Andrew W.

Abstract

dlmap is a software package capable of mapping quantitative trait loci (QTL) in a variety of genetic studies. Unlike most other QTL mapping packages, dlmap is built on a linear mixed model platform, and thus can simultaneously handle multiple sources of genetic and environmental variation. Furthermore, it can accommodate both experimental crosses and association mapping populations within a versatile modeling framework. The software implements a mapping algorithm with separate detection and localization stages in a user-friendly manner. It accepts data in various common formats, has a flexible modeling environment, and summarizes results both graphically and numerically.

Suggested Citation

  • Huang, B. Emma & Shah, Rohan & George, Andrew W., 2012. "dlmap: An R Package for Mixed Model QTL and Association Analysis," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 50(i06).
    • Handle: RePEc:jss:jstsof:v:050:i06
    DOI: http://hdl.handle.net/10.18637/jss.v050.i06
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    References listed on IDEAS

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    1. Gilmour, A.R., 2007. "Mixed model regression mapping for QTL detection in experimental crosses," Computational Statistics & Data Analysis, Elsevier, vol. 51(8), pages 3749-3764, May.
    2. Taylor, Julian & Verbyla, Arunas, 2011. "R Package wgaim: QTL Analysis in Bi-Parental Populations Using Linear Mixed Models," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 40(i07).
    3. Karl W. Broman & Terence P. Speed, 2002. "A model selection approach for the identification of quantitative trait loci in experimental crosses," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 64(4), pages 641-656, October.
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