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Comprehensive Review of Chronic Stress Pathways and the Efficacy of Behavioral Stress Reduction Programs (BSRPs) in Managing Diseases

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  • Aladdin Y. Shchaslyvyi

    (Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150, Zabolotnogo Str., 03143 Kyiv, Ukraine)

  • Svitlana V. Antonenko

    (Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150, Zabolotnogo Str., 03143 Kyiv, Ukraine)

  • Gennadiy D. Telegeev

    (Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150, Zabolotnogo Str., 03143 Kyiv, Ukraine)

Abstract

The connection between chronic psychological stress and the onset of various diseases, including diabetes, HIV, cancer, and cardiovascular conditions, is well documented. This review synthesizes current research on the neurological, immune, hormonal, and genetic pathways through which stress influences disease progression, affecting multiple body systems: nervous, immune, cardiovascular, respiratory, reproductive, musculoskeletal, and integumentary. Central to this review is an evaluation of 16 Behavioral Stress Reduction Programs (BSRPs) across over 200 studies, assessing their effectiveness in mitigating stress-related health outcomes. While our findings suggest that BSRPs have the potential to enhance the effectiveness of medical therapies and reverse disease progression, the variability in study designs, sample sizes, and methodologies raises questions about the generalizability and robustness of these results. Future research should focus on long-term, large-scale studies with rigorous methodologies to validate the effectiveness of BSRPs.

Suggested Citation

  • Aladdin Y. Shchaslyvyi & Svitlana V. Antonenko & Gennadiy D. Telegeev, 2024. "Comprehensive Review of Chronic Stress Pathways and the Efficacy of Behavioral Stress Reduction Programs (BSRPs) in Managing Diseases," IJERPH, MDPI, vol. 21(8), pages 1-57, August.
    • Handle: RePEc:gam:jijerp:v:21:y:2024:i:8:p:1077-:d:1457833
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    References listed on IDEAS

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    1. Khadija El Aoufy & Arianna Pezzutto & Alessandra Pollina & Laura Rasero & Stefano Bambi & Silvia Bellando-Randone & Serena Guiducci & Susanna Maddali-Bongi & Marco Matucci Cerinic, 2023. "Systemic Sclerosis Patients Experiencing Mindfulness-Based Stress Reduction Program: The Beneficial Effect on Their Psychological Status and Quality of Life," IJERPH, MDPI, vol. 20(3), pages 1-10, January.
    2. Alessandra Accoto & Salvatore Gaetano Chiarella & Antonino Raffone & Antonella Montano & Adriano de Marco & Francesco Mainiero & Roberta Rubbino & Alessandro Valzania & David Conversi, 2021. "Beneficial Effects of Mindfulness-Based Stress Reduction Training on the Well-Being of a Female Sample during the First Total Lockdown Due to COVID-19 Pandemic in Italy," IJERPH, MDPI, vol. 18(11), pages 1-18, May.
    3. Kate E. Coleman & Yandong Yin & Sarah Kit Leng Lui & Sarah Keegan & David Fenyo & Duncan J. Smith & Eli Rothenberg & Tony T. Huang, 2022. "USP1-trapping lesions as a source of DNA replication stress and genomic instability," Nature Communications, Nature, vol. 13(1), pages 1-19, December.
    4. Huimin Li & Xinyue Ma & Jie Fang & Getian Liang & Rongsheng Lin & Weiyan Liao & Xuesong Yang, 2022. "Student Stress and Online Shopping Addiction Tendency among College Students in Guangdong Province, China: The Mediating Effect of the Social Support," IJERPH, MDPI, vol. 20(1), pages 1-12, December.
    5. Ran Wu & Hong Zhu & Meng-Yang Wu & Guang-Hai Wang & Chun-Lei Jiang, 2022. "Childhood Trauma and Suicide: The Mediating Effect of Stress and Sleep," IJERPH, MDPI, vol. 19(14), pages 1-11, July.
    6. Ae Sil Kim & Mi Heui Jang & Min Jung Sun, 2021. "Effects of Mindfulness-Based Stress Reduction (MBSR) on Stress, Heart Rate Variability, Affect, and Wellbeing among People with Schizophrenia," IJERPH, MDPI, vol. 18(22), pages 1-14, November.
    7. María del Carmen Rodríguez-Martínez & Alba De la Plana Maestre & Juan Antonio Armenta-Peinado & Miguel Ángel Barbancho & Natalia García-Casares, 2021. "Evidence of Animal-Assisted Therapy in Neurological Diseases in Adults: A Systematic Review," IJERPH, MDPI, vol. 18(24), pages 1-17, December.
    8. Williams, J.K. & Glover, D.A. & Wyatt, G.E. & Kisler, K. & Liu, H. & Zhang, M., 2013. "A sexual risk and stress reduction intervention designed for HIV-positive bisexual African American men with childhood sexual abuse histories," American Journal of Public Health, American Public Health Association, vol. 103(8), pages 1476-1484.
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