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Anxiety and Depression Disorders in Undergraduate Medical Students During the COVID-19 Pandemic: An Integrative Literature Review

Author

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  • Ana Luisa Varrone Sartorao

    (Faculty of Medicine, Educational Foundation of the Municipality of Assis., São Paulo 19815-110, Brazil)

  • Carlos Izaias Sartorao-Filho

    (Faculty of Medicine, Educational Foundation of the Municipality of Assis., São Paulo 19815-110, Brazil)

Abstract

Introduction: The COVID-19 pandemic has triggered several challenges on the front of mental health. Undergraduate medical students face considerable stress in their academic routines. Thus, there is a need to explore the implications for the mental health of undergraduate medical students during the COVID-19 pandemic. Objective: To review the global literature about anxiety and depressive disorders in undergraduate medical students during the COVID-19 pandemic. Method: We developed an integrative literature review on the occurrence of anxiety and depressive symptoms in undergraduate medical students during the COVID-19 pandemic. We included the manuscripts that used the PHQ-9 and/or GAD-7 questionnaires. We excluded systematic reviews, narrative reviews, integrative reviews, meta-analyses, and qualitative analytical studies. We assessed the results on the occurrence of anxiety and depression and the severity of symptoms in medical students during the COVID-19 pandemic using quantitative studies applying the GAD-7 questionnaire for anxiety or the PHQ-9 for depression. Results: We reviewed 85 selected studies, and the results showed a significant prevalence of moderate and severe symptoms of anxiety and depression, with 28.2% of participants presenting scores of ≥10 on the GAD-7 and 38.9% on the PHQ-9. Statistical analyses using simple and multiple regression tests revealed associations between higher rates of anxiety symptoms among students from developing countries and data collected after the lockdown period in 2020 during the pandemic lockdown. In addition, female students were at risk of depressive disorders. We emphasize as a limitation that the diagnosis of depression and anxiety requires a detailed clinical evaluation, which is not focused on in this actual study. Conclusions: Our findings highlight the need for specific interventions to support the mental health of undergraduate medical students, especially female students from developing countries, during a pandemic crisis.

Suggested Citation

  • Ana Luisa Varrone Sartorao & Carlos Izaias Sartorao-Filho, 2024. "Anxiety and Depression Disorders in Undergraduate Medical Students During the COVID-19 Pandemic: An Integrative Literature Review," IJERPH, MDPI, vol. 21(12), pages 1-15, December.
    • Handle: RePEc:gam:jijerp:v:21:y:2024:i:12:p:1620-:d:1536090
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    References listed on IDEAS

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    1. Cuiyan Wang & Riyu Pan & Xiaoyang Wan & Yilin Tan & Linkang Xu & Cyrus S. Ho & Roger C. Ho, 2020. "Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China," IJERPH, MDPI, vol. 17(5), pages 1-25, March.
    2. Huidi Xiao & Wen Shu & Menglong Li & Ziang Li & Fangbiao Tao & Xiaoyan Wu & Yizhen Yu & Heng Meng & Sten H. Vermund & Yifei Hu, 2020. "Social Distancing among Medical Students during the 2019 Coronavirus Disease Pandemic in China: Disease Awareness, Anxiety Disorder, Depression, and Behavioral Activities," IJERPH, MDPI, vol. 17(14), pages 1-13, July.
    3. Fan Wu & Su Zhao & Bin Yu & Yan-Mei Chen & Wen Wang & Zhi-Gang Song & Yi Hu & Zhao-Wu Tao & Jun-Hua Tian & Yuan-Yuan Pei & Ming-Li Yuan & Yu-Ling Zhang & Fa-Hui Dai & Yi Liu & Qi-Min Wang & Jiao-Jiao , 2020. "A new coronavirus associated with human respiratory disease in China," Nature, Nature, vol. 579(7798), pages 265-269, March.
    4. Fan Wu & Su Zhao & Bin Yu & Yan-Mei Chen & Wen Wang & Zhi-Gang Song & Yi Hu & Zhao-Wu Tao & Jun-Hua Tian & Yuan-Yuan Pei & Ming-Li Yuan & Yu-Ling Zhang & Fa-Hui Dai & Yi Liu & Qi-Min Wang & Jiao-Jiao , 2020. "Author Correction: A new coronavirus associated with human respiratory disease in China," Nature, Nature, vol. 580(7803), pages 7-7, April.
    5. Alyssa A. Guo & Marissa A. Crum & Lauren A. Fowler, 2021. "Assessing the Psychological Impacts of COVID-19 in Undergraduate Medical Students," IJERPH, MDPI, vol. 18(6), pages 1-14, March.
    6. Esperanza L. Gómez-Durán & Carles Martin Fumadó & Aina M. Gassó & Sandra Díaz & Andrea Miranda-Mendizabal & Carlos G. Forero & Montserrat Virumbrales, 2022. "COVID-19 Pandemic Psychological Impact and Volunteering Experience Perceptions of Medical Students after 2 Years," IJERPH, MDPI, vol. 19(12), pages 1-12, June.
    7. Zahra Alsairafi & Abdallah Y. Naser & Fatemah M. Alsaleh & Abdelmoneim Awad & Zahraa Jalal, 2021. "Mental Health Status of Healthcare Professionals and Students of Health Sciences Faculties in Kuwait during the COVID-19 Pandemic," IJERPH, MDPI, vol. 18(4), pages 1-15, February.
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