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Methods and Strategies for Biomonitoring in Occupational Exposure to Plant Protection Products Containing Glyphosate

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  • Horațiu Moldovan

    (Department of Occupational Medicine, Faculty of Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology, 540142 Târgu Mureş, Romania)

  • Silvia Imre

    (Center for Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science, and Technology, 540142 Târgu Mureş, Romania
    Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science, and Technology, 540142 Târgu Mureş, Romania)

  • Radu Corneliu Duca

    (Environmental Hygiene and Biological Monitoring Unit, Department of Health Protection, National Health Laboratory (LNS), 3555 Dudelange, Luxembourg)

  • Lénárd Farczádi

    (Center for Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science, and Technology, 540142 Târgu Mureş, Romania)

Abstract

Glyphosate, and the ever growing reliance on its use in agriculture, has been a point of contention for many years. There have been debates regarding the risk and safety of using glyphosate-based herbicides as well as the effects of occupational, accidental, or systematic. Although there have been a number of studies conducted, the biomonitoring of glyphosate poses a series of challenges. Researchers attempting to determine the occupational exposure face questions regarding the most appropriate analytical techniques and sampling procedures. The present review aims to summarize and synthetize the analytical methodologies available and suitable for the purpose of glyphosate biomonitoring studies as well as discuss the advantages and disadvantages of each analytical technique, from the most modern to more well-established and older ones. The most relevant publications that have described analytical methods and published within the last 12 years were studied. Methods were compared, and the advantages and disadvantages of each methods were discussed. A total of 35 manuscripts describing analytical methods for glyphosate determination were summarized and discussed, with the most relevant one being compared. For methods that were not intended for biological samples, we discussed if they could be used for biomonitoring and approaches to adapt these methods for this purpose.

Suggested Citation

  • Horațiu Moldovan & Silvia Imre & Radu Corneliu Duca & Lénárd Farczádi, 2023. "Methods and Strategies for Biomonitoring in Occupational Exposure to Plant Protection Products Containing Glyphosate," IJERPH, MDPI, vol. 20(4), pages 1-15, February.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:4:p:3314-:d:1067652
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    References listed on IDEAS

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    1. Jaime Rendon-von Osten & Ricardo Dzul-Caamal, 2017. "Glyphosate Residues in Groundwater, Drinking Water and Urine of Subsistence Farmers from Intensive Agriculture Localities: A Survey in Hopelchén, Campeche, Mexico," IJERPH, MDPI, vol. 14(6), pages 1-13, June.
    2. Clémentine Antier & Per Kudsk & Xavier Reboud & Lena Ulber & Philippe V. Baret & Antoine Messéan, 2020. "Glyphosate Use in the European Agricultural Sector and a Framework for Its Further Monitoring," Sustainability, MDPI, vol. 12(14), pages 1-22, July.
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    Cited by:

    1. José Belisario Leyva-Morales & Rosina Cabrera & Pedro de Jesús Bastidas-Bastidas & Ana Isabel Valenzuela-Quintanar & Juan Pablo Pérez-Camarillo & Víctor Manuel González-Mendoza & Xiomara Patricia Pere, 2023. "Validation and Application of Liquid Chromatography Coupled with Tandem Mass Spectrometry Method for the Analysis of Glyphosate, Aminomethylphosphonic Acid (AMPA), and Glufosinate in Soil," Agriculture, MDPI, vol. 13(6), pages 1-17, May.

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