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Trends in the Prevalence of Cardiometabolic Multimorbidity in the United States, 1999–2018

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  • Xunjie Cheng

    (Department of Geriatric Medicine, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha 410008, China
    National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China
    These authors contributed equally to this work.)

  • Tianqi Ma

    (Department of Geriatric Medicine, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha 410008, China
    National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China
    These authors contributed equally to this work.)

  • Feiyun Ouyang

    (Department of Social Medicine and Health Management, Central South University, Changsha 410078, China)

  • Guogang Zhang

    (Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha 410008, China
    Department of Cardiovascular Medicine, The Third Xiangya Hospital, Central South University, Changsha 410013, China)

  • Yongping Bai

    (Department of Geriatric Medicine, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha 410008, China
    National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China)

Abstract

Cardiometabolic multimorbidity (co-existence of ≥1 cardiometabolic diseases) is increasingly common, while its prevalence in the U.S. is unknown. We utilized data from 10 National Health and Nutrition Examination Survey (NHANES) two-year cycles in U.S. adults from 1999 to 2018. We reported the age-standardized prevalence of cardiometabolic multimorbidity in 2017–2018 and analyzed their trends during 1999–2018 with joinpoint regression models. Stratified analyses were performed according to gender, age, and race/ethnicity. In 2017–2018, the prevalence of cardiometabolic multimorbidity was 14.4% in the U.S., and it was higher among male, older, and non-Hispanic Black people. The three most common patterns were hypertension and diabetes (7.5%); hypertension, diabetes, and CHD (2.2%); and hypertension and CHD (1.8%). During 1999–2018, the prevalence of cardiometabolic multimorbidity in U.S. adults increased significantly, with an averaged two-year cycle percentage change (AAPC) of 3.6 (95% CI: 2.1 to 5.3). The increasing trend was significant for both genders, most age groups except for 60–79 years, and non-Hispanic White people. For common patterns, the trend was increasing for hypertension and diabetes and hypertension, diabetes, and CHD, while it was decreasing for hypertension and CHD. Our findings provide evidence that cardiometabolic multimorbidity has risen as an austere issue of public health in the U.S.

Suggested Citation

  • Xunjie Cheng & Tianqi Ma & Feiyun Ouyang & Guogang Zhang & Yongping Bai, 2022. "Trends in the Prevalence of Cardiometabolic Multimorbidity in the United States, 1999–2018," IJERPH, MDPI, vol. 19(8), pages 1-12, April.
  • Handle: RePEc:gam:jijerp:v:19:y:2022:i:8:p:4726-:d:793500
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    References listed on IDEAS

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    1. Archana Singh-Manoux & Aurore Fayosse & Séverine Sabia & Adam Tabak & Martin Shipley & Aline Dugravot & Mika Kivimäki, 2018. "Clinical, socioeconomic, and behavioural factors at age 50 years and risk of cardiometabolic multimorbidity and mortality: A cohort study," PLOS Medicine, Public Library of Science, vol. 15(5), pages 1-16, May.
    2. Grzegorz K. Jakubiak & Natalia Pawlas & Grzegorz Cieślar & Agata Stanek, 2021. "Pathogenesis and Clinical Significance of In-Stent Restenosis in Patients with Diabetes," IJERPH, MDPI, vol. 18(22), pages 1-23, November.
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