IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i6p3731-d776044.html
   My bibliography  Save this article

Quality of Life in Patients with Pancreatic Cancer before and during the COVID-19 Pandemic

Author

Listed:
  • Andrea Alexander

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany
    These authors contributed equally to this work.)

  • Stephen Fung

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany
    These authors contributed equally to this work.)

  • Martin Eichler

    (Clinic and Polyclinic for Internal Medicine I, University Hospital Carl Gustav Carus Dresden, 01307 Dresden, Germany)

  • Nadja Lehwald-Tywuschik

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany)

  • Vasuki Uthayakumar

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany)

  • Sami-Alexander Safi

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany)

  • Christian Vay

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany)

  • Hany Ashmawy

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany)

  • Sinan Kalmuk

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany)

  • Alexander Rehders

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany)

  • Sascha Vaghiri

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany)

  • Wolfram Trudo Knoefel

    (Department of General, Visceral and Pediatric Surgery, University Hospital Düsseldorf and Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Duesseldorf, Germany)

Abstract

Background: Coronavirus disease 19 (COVID-19) substantially affects cancer patients due to adverse outcomes and disruptions in cancer care. Recent studies have indicated the additional stress and anxiety burden arising from the pandemic and impairing quality of life in this vulnerable group of patients. However, patients with cancer represent a heterogenous group. Therefore, we conducted a study on patients with pancreatic cancer, requiring demanding surgical interventions and chemotherapy regimens due to its aggressive tumor biology, to explore the pandemic’s impact on quality of life within this homogenous cohort. Methods: In a descriptive observational study, the quality of life of patients who had undergone pancreatic surgery for tumor resection at our institution between 2014 and the beginning of the pandemic in March 2020 was assessed. For HRQoL measurement, we used the European Organisation for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30), comparing their situation before the pandemic and since its beginning. An additional self-developed questionnaire was applied to assess the life circumstances during the pandemic. Results: Our cohort included 26 patients. Scores from the survey in HRQoL revealed no significant changes over time between before and during the pandemic. A medium deterioration in HRQoL was apparent in social functioning, as well as a small deterioration in role functioning and emotional functioning. Worries concerning a potential impact of COVID-19 on personal health were expressed. Psychological limitations in QoL were mainly attributed to the pandemic, whereas physical limitations in QoL were rather associated with the underlying disease of pancreatic cancer. Conclusion: The COVID-19 pandemic is causing considerable social and emotional distress among pancreatic cancer patients. These patients will benefit from psychological support during the pandemic and beyond. Long-time survivors of pancreatic cancer, such as those included in our cohort, appear to have improved resilience facing the psychosocial challenges of the pandemic. For pancreatic cancer, surgical care is considered the cornerstone of treatment. Prolonged delays in healthcare cause serious damage to mental and physical health. To date, the longer-term clinical consequences are not known and can only be estimated. The potential tragic outcome for the vulnerable group of pancreatic cancer patients highlights the urgency of timely healthcare decisions to be addressed in the future.

Suggested Citation

  • Andrea Alexander & Stephen Fung & Martin Eichler & Nadja Lehwald-Tywuschik & Vasuki Uthayakumar & Sami-Alexander Safi & Christian Vay & Hany Ashmawy & Sinan Kalmuk & Alexander Rehders & Sascha Vaghiri, 2022. "Quality of Life in Patients with Pancreatic Cancer before and during the COVID-19 Pandemic," IJERPH, MDPI, vol. 19(6), pages 1-10, March.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:6:p:3731-:d:776044
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/6/3731/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/6/3731/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Cuiyan Wang & Riyu Pan & Xiaoyang Wan & Yilin Tan & Linkang Xu & Cyrus S. Ho & Roger C. Ho, 2020. "Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China," IJERPH, MDPI, vol. 17(5), pages 1-25, March.
    2. Diana Frasquilho & Ricardo Matias & Jaime Grácio & Berta Sousa & Fernando Luís-Ferreira & João Leal & Fátima Cardoso & Albino J. Oliveira-Maia, 2021. "Protocol for the Implementation and Assessment of “MoodUP”: A Stepped Care Model Assisted by a Digital Platform to Accelerate Access to Mental Health Care for Cancer Patients Amid the COVID-19 Pandemi," IJERPH, MDPI, vol. 18(9), pages 1-11, April.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Yuchen Lu, 2024. "Uncovering the Barriers to Foreign Residents' Enrollment in Japan's National Health Insurance: An Econometric Analysis Using Pooled Cross-Sectional Data," Keio-IES Discussion Paper Series 2024-026, Institute for Economics Studies, Keio University.
    2. Rocío Lavigne-Cervan & Borja Costa-López & Rocío Juárez-Ruiz de Mier & Marta Sánchez-Muñoz de León & Marta Real-Fernández & Ignasi Navarro-Soria, 2021. "Implications of the Online Teaching Model Derived from the COVID-19 Lockdown Situation for Anxiety and Executive Functioning in Spanish Children and Adolescents," IJERPH, MDPI, vol. 18(19), pages 1-15, October.
    3. Fei Qin & Yiqing Song & George P Nassis & Lina Zhao & Yanan Dong & Cuicui Zhao & Yiwei Feng & Jiexiu Zhao, 2020. "Physical Activity, Screen Time, and Emotional Well-Being during the 2019 Novel Coronavirus Outbreak in China," IJERPH, MDPI, vol. 17(14), pages 1-16, July.
    4. Na-Hye Kim & Jung-Min Lee & Eunhye Yoo, 2022. "How the COVID-19 Pandemic Has Changed Adolescent Health: Physical Activity, Sleep, Obesity, and Mental Health," IJERPH, MDPI, vol. 19(15), pages 1-12, July.
    5. Xinqiao Liu & Yifan Zhang & Wenjuan Gao & Xiaojie Cao, 2023. "Developmental trajectories of depression, anxiety, and stress among college students: a piecewise growth mixture model analysis," Palgrave Communications, Palgrave Macmillan, vol. 10(1), pages 1-10, December.
    6. Gina Voss & Andreia F. Paiva & Alice Delerue Matos, 2021. "A Study of the Association between the Stringency of Covid-19 Government Measures and Depression in Older Adults across Europe and Israel," IJERPH, MDPI, vol. 18(15), pages 1-12, July.
    7. Mateusz Ciski & Krzysztof Rząsa, 2023. "Multiscale Geographically Weighted Regression in the Investigation of Local COVID-19 Anomalies Based on Population Age Structure in Poland," IJERPH, MDPI, vol. 20(10), pages 1-23, May.
    8. José Pais-Ribeiro & Alexandra Ferreira-Valente & Margarida Jarego & Elisabet Sánchez-Rodríguez & Jordi Miró, 2022. "COVID-19 Pandemic in Portugal: Psychosocial and Health-Related Factors Associated with Psychological Discomfort," IJERPH, MDPI, vol. 19(6), pages 1-13, March.
    9. Alessandro Germani & Livia Buratta & Elisa Delvecchio & Claudia Mazzeschi, 2020. "Emerging Adults and COVID-19: The Role of Individualism-Collectivism on Perceived Risks and Psychological Maladjustment," IJERPH, MDPI, vol. 17(10), pages 1-15, May.
    10. Joanna Baj-Korpak & Kamil Zaworski & Ewa Szymczuk & Andrei Shpakou, 2022. "Physical Activity and Mental Health of Medical Students from Poland and Belarus-Countries with Different Restrictive Approaches during the COVID-19 Pandemic," IJERPH, MDPI, vol. 19(21), pages 1-15, October.
    11. Gülsen Erden & Asil Ali Özdoğru & Sami Çoksan & Hale Ögel-Balaban & Yakup Azak & İlkiz Altınoğlu-Dikmeer & Aysun Ergül-Topçu & Yeşim Yasak & Gözde Kıral-Uçar & Seda Oktay & Pelin Karaca-Dinç & Ezgi Di, 2022. "Social Contact, Academic Satisfaction, COVID-19 Knowledge, and Subjective Well-being Among Students at Turkish Universities: a Nine-University Sample," Applied Research in Quality of Life, Springer;International Society for Quality-of-Life Studies, vol. 17(4), pages 2017-2039, August.
    12. Mevlut Okan Aydin & Guven Ozkaya & Ilker Mustafa Kafa & Shafiul Haque & Zuleyha Alper, 2023. "Hopelessness among Medical Students Caused Due to COVID-19 Pandemic Linked Educational Hiatus: A Case Study of Bursa Uludag University, Türkiye," Sustainability, MDPI, vol. 15(4), pages 1-15, February.
    13. Gregory Knell & Michael C. Robertson & Erin E. Dooley & Katie Burford & Karla S. Mendez, 2020. "Health Behavior Changes During COVID-19 Pandemic and Subsequent “Stay-at-Home” Orders," IJERPH, MDPI, vol. 17(17), pages 1-16, August.
    14. Chunli Wei & Qingqing Li & Ziyi Lian & Yijun Luo & Shiqing Song & Hong Chen, 2022. "Variation in Public Trust, Perceived Societal Fairness, and Well-Being before and after COVID-19 Onset—Evidence from the China Family Panel Studies," IJERPH, MDPI, vol. 19(19), pages 1-14, September.
    15. Edmond Pui Hang Choi & Bryant Pui Hung Hui & Eric Yuk Fai Wan & Jojo Yan Yan Kwok & Tiffany Hei Lam Tam & Chanchan Wu, 2021. "COVID-19 and Health-Related Quality of Life: A Community-Based Online Survey in Hong Kong," IJERPH, MDPI, vol. 18(6), pages 1-12, March.
    16. Valerie Bauza & Gloria D. Sclar & Alokananda Bisoyi & Ajilé Owens & Apurva Ghugey & Thomas Clasen, 2021. "Experience of the COVID-19 Pandemic in Rural Odisha, India: Knowledge, Preventative Actions, and Impacts on Daily Life," IJERPH, MDPI, vol. 18(6), pages 1-17, March.
    17. Antonio José Sánchez-Guarnido & Nuria Hidalgo & Jorge Arenas de la Cruz & Inmaculada Esteban & Silvia Mondón & Carlos Herruzo, 2021. "Analysis of the Consequences of the COVID-19 Pandemic on People with Severe Mental Disorders," IJERPH, MDPI, vol. 18(16), pages 1-11, August.
    18. Mohamed Mekhemar & Sameh Attia & Christof Dörfer & Jonas Conrad, 2021. "Dental Nurses’ Mental Health in Germany: A Nationwide Survey during the COVID-19 Pandemic," IJERPH, MDPI, vol. 18(15), pages 1-18, July.
    19. Ana María Recio-Vivas & José Miguel Mansilla-Domíngez & Ángel Belzunegui-Eraso & David Peña-Otero & David Díaz-Pérez & Laura Lorenzo-Allegue & Isabel Font-Jiménez, 2022. "Compliance with COVID-19 Prevention Measures in the Spanish Population during the New Normal: Will the Need for Greater Community Involvement Be One of the Lessons Learned?," IJERPH, MDPI, vol. 19(23), pages 1-11, November.
    20. Marwah Ahmed Behisi & Hussain M. Altaweel & Reham F. Gassas & Mansour Aldehaiman & Abdulmajeed A. Alkhamees, 2021. "COVID-19 Pandemic and Mental Health Status of Saudi Citizens Living Abroad," IJERPH, MDPI, vol. 18(15), pages 1-17, July.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:6:p:3731-:d:776044. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.