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Obesity and Thyroid Cancer Risk: An Update

Author

Listed:
  • Fabiana Franchini

    (Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Napoli, Italy
    These authors equally contributed to the work.)

  • Giuseppe Palatucci

    (Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Napoli, Italy
    These authors equally contributed to the work.)

  • Annamaria Colao

    (Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Napoli, Italy)

  • Paola Ungaro

    (National Research Council–Institute for Experimental Endocrinology & Oncology ‘Gaetano Salvatore’, 80145 Napoli, Italy)

  • Paolo Emidio Macchia

    (Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Napoli, Italy)

  • Immacolata Cristina Nettore

    (Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Napoli, Italy)

Abstract

Thyroid cancer (TC) is the most common endocrine malignancy worldwide and its incidence has increased dramatically in recent years. In parallel, the prevalence of overweight and obesity has also increased, suggesting a possible link between these two diseases. Indeed, low-grade chronic inflammation, altered cytokine levels, insulin resistance, oxidative stress, and hormonal changes that occur in obese patients are all factors that contribute to the occurrence and growth of TC. In this review, the most recent evidence supporting the potential role of the mechanisms linking obesity to TC will be discussed.

Suggested Citation

  • Fabiana Franchini & Giuseppe Palatucci & Annamaria Colao & Paola Ungaro & Paolo Emidio Macchia & Immacolata Cristina Nettore, 2022. "Obesity and Thyroid Cancer Risk: An Update," IJERPH, MDPI, vol. 19(3), pages 1-15, January.
  • Handle: RePEc:gam:jijerp:v:19:y:2022:i:3:p:1116-:d:728945
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    References listed on IDEAS

    as
    1. Immacolata Cristina Nettore & Annamaria Colao & Paolo Emidio Macchia, 2018. "Nutritional and Environmental Factors in Thyroid Carcinogenesis," IJERPH, MDPI, vol. 15(8), pages 1-11, August.
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