IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i1p480-d716349.html
   My bibliography  Save this article

Disease Progression Detection via Deep Sequence Learning of Successive Radiographic Scans

Author

Listed:
  • Jamil Ahmad

    (Department of Computer Science, Islamia College Peshawar, Chartered University, Peshawar 25000, Pakistan)

  • Abdul Khader Jilani Saudagar

    (Information Systems Department, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia)

  • Khalid Mahmood Malik

    (Department of Computer Science and Engineering, Oakland University, Rochester, MI 48309, USA)

  • Waseem Ahmad

    (Lady Reading Hospital-Medical Teaching Institute, Peshawar 25000, Pakistan)

  • Muhammad Badruddin Khan

    (Information Systems Department, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia)

  • Mozaherul Hoque Abul Hasanat

    (Information Systems Department, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia)

  • Abdullah AlTameem

    (Information Systems Department, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia)

  • Mohammed AlKhathami

    (Information Systems Department, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia)

  • Muhammad Sajjad

    (Department of Computer Science, Islamia College Peshawar, Chartered University, Peshawar 25000, Pakistan)

Abstract

The highly rapid spread of the current pandemic has quickly overwhelmed hospitals all over the world and motivated extensive research to address a wide range of emerging problems. The unforeseen influx of COVID-19 patients to hospitals has made it inevitable to deploy a rapid and accurate triage system, monitor progression, and predict patients at higher risk of deterioration in order to make informed decisions regarding hospital resource management. Disease detection in radiographic scans, severity estimation, and progression and prognosis prediction have been extensively studied with the help of end-to-end methods based on deep learning. The majority of recent works have utilized a single scan to determine severity or predict progression of the disease. In this paper, we present a method based on deep sequence learning to predict improvement or deterioration in successive chest X-ray scans and build a mathematical model to determine individual patient disease progression profile using successive scans. A deep convolutional neural network pretrained on a diverse lung disease dataset was used as a feature extractor to generate the sequences. We devised three strategies for sequence modeling in order to obtain both fine-grained and coarse-grained features and construct sequences of different lengths. We also devised a strategy to quantify positive or negative change in successive scans, which was then combined with age-related risk factors to construct disease progression profile for COVID-19 patients. The age-related risk factors allowed us to model rapid deterioration and slower recovery in older patients. Experiments conducted on two large datasets showed that the proposed method could accurately predict disease progression. With the best feature extractor, the proposed method was able to achieve AUC of 0.98 with the features obtained from radiographs. Furthermore, the proposed patient profiling method accurately estimated the health profile of patients.

Suggested Citation

  • Jamil Ahmad & Abdul Khader Jilani Saudagar & Khalid Mahmood Malik & Waseem Ahmad & Muhammad Badruddin Khan & Mozaherul Hoque Abul Hasanat & Abdullah AlTameem & Mohammed AlKhathami & Muhammad Sajjad, 2022. "Disease Progression Detection via Deep Sequence Learning of Successive Radiographic Scans," IJERPH, MDPI, vol. 19(1), pages 1-16, January.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:1:p:480-:d:716349
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/1/480/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/1/480/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Andre Esteva & Brett Kuprel & Roberto A. Novoa & Justin Ko & Susan M. Swetter & Helen M. Blau & Sebastian Thrun, 2017. "Correction: Corrigendum: Dermatologist-level classification of skin cancer with deep neural networks," Nature, Nature, vol. 546(7660), pages 686-686, June.
    2. Andre Esteva & Brett Kuprel & Roberto A. Novoa & Justin Ko & Susan M. Swetter & Helen M. Blau & Sebastian Thrun, 2017. "Dermatologist-level classification of skin cancer with deep neural networks," Nature, Nature, vol. 542(7639), pages 115-118, February.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Lin Lu & Laurent Dercle & Binsheng Zhao & Lawrence H. Schwartz, 2021. "Deep learning for the prediction of early on-treatment response in metastatic colorectal cancer from serial medical imaging," Nature Communications, Nature, vol. 12(1), pages 1-11, December.
    2. Zheng Yan & Wenqian Robertson & Yaosheng Lou & Tom W. Robertson & Sung Yong Park, 2021. "Finding leading scholars in mobile phone behavior: a mixed-method analysis of an emerging interdisciplinary field," Scientometrics, Springer;Akadémiai Kiadó, vol. 126(12), pages 9499-9517, December.
    3. Freddy Gabbay & Rotem Lev Aharoni & Ori Schweitzer, 2022. "Deep Neural Network Memory Performance and Throughput Modeling and Simulation Framework," Mathematics, MDPI, vol. 10(21), pages 1-20, November.
    4. Jungyoon Kim & Jihye Lim, 2021. "A Deep Neural Network-Based Method for Prediction of Dementia Using Big Data," IJERPH, MDPI, vol. 18(10), pages 1-13, May.
    5. Gang Yu & Kai Sun & Chao Xu & Xing-Hua Shi & Chong Wu & Ting Xie & Run-Qi Meng & Xiang-He Meng & Kuan-Song Wang & Hong-Mei Xiao & Hong-Wen Deng, 2021. "Accurate recognition of colorectal cancer with semi-supervised deep learning on pathological images," Nature Communications, Nature, vol. 12(1), pages 1-13, December.
    6. DonHee Lee & Seong No Yoon, 2021. "Application of Artificial Intelligence-Based Technologies in the Healthcare Industry: Opportunities and Challenges," IJERPH, MDPI, vol. 18(1), pages 1-18, January.
    7. Claus Zippel & Sabine Bohnet-Joschko, 2021. "Rise of Clinical Studies in the Field of Machine Learning: A Review of Data Registered in ClinicalTrials.gov," IJERPH, MDPI, vol. 18(10), pages 1-14, May.
    8. Dario Sipari & Betsy D. M. Chaparro-Rico & Daniele Cafolla, 2022. "SANE (Easy Gait Analysis System): Towards an AI-Assisted Automatic Gait-Analysis," IJERPH, MDPI, vol. 19(16), pages 1-27, August.
    9. Rasheed Omobolaji Alabi & Alhadi Almangush & Mohammed Elmusrati & Ilmo Leivo & Antti Mäkitie, 2022. "Measuring the Usability and Quality of Explanations of a Machine Learning Web-Based Tool for Oral Tongue Cancer Prognostication," IJERPH, MDPI, vol. 19(14), pages 1-13, July.
    10. Andreas Fügener & Jörn Grahl & Alok Gupta & Wolfgang Ketter, 2022. "Cognitive Challenges in Human–Artificial Intelligence Collaboration: Investigating the Path Toward Productive Delegation," Information Systems Research, INFORMS, vol. 33(2), pages 678-696, June.
    11. Vidhya V. & Anjan Gudigar & U. Raghavendra & Ajay Hegde & Girish R. Menon & Filippo Molinari & Edward J. Ciaccio & U. Rajendra Acharya, 2021. "Automated Detection and Screening of Traumatic Brain Injury (TBI) Using Computed Tomography Images: A Comprehensive Review and Future Perspectives," IJERPH, MDPI, vol. 18(12), pages 1-29, June.
    12. Pujin Wang & Jianzhuang Xiao & Ken’ichi Kawaguchi & Lichen Wang, 2022. "Automatic Ceiling Damage Detection in Large-Span Structures Based on Computer Vision and Deep Learning," Sustainability, MDPI, vol. 14(6), pages 1-24, March.
    13. Xu Gong & Keqin Guan & Qiyang Chen, 2022. "The role of textual analysis in oil futures price forecasting based on machine learning approach," Journal of Futures Markets, John Wiley & Sons, Ltd., vol. 42(10), pages 1987-2017, October.
    14. Julian Schiele & Thomas Koperna & Jens O. Brunner, 2021. "Predicting intensive care unit bed occupancy for integrated operating room scheduling via neural networks," Naval Research Logistics (NRL), John Wiley & Sons, vol. 68(1), pages 65-88, February.
    15. Kai Feng & Han Hong & Ke Tang & Jingyuan Wang, 2023. "Statistical Tests for Replacing Human Decision Makers with Algorithms," Papers 2306.11689, arXiv.org.
    16. He, Wenbin & Liu, Ting & Ming, Wuyi & Li, Zongze & Du, Jinguang & Li, Xiaoke & Guo, Xudong & Sun, Peiyan, 2024. "Progress in prediction of remaining useful life of hydrogen fuel cells based on deep learning," Renewable and Sustainable Energy Reviews, Elsevier, vol. 192(C).
    17. Oded Rotem & Tamar Schwartz & Ron Maor & Yishay Tauber & Maya Tsarfati Shapiro & Marcos Meseguer & Daniella Gilboa & Daniel S. Seidman & Assaf Zaritsky, 2024. "Visual interpretability of image-based classification models by generative latent space disentanglement applied to in vitro fertilization," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
    18. Zhiming Cui & Yu Fang & Lanzhuju Mei & Bojun Zhang & Bo Yu & Jiameng Liu & Caiwen Jiang & Yuhang Sun & Lei Ma & Jiawei Huang & Yang Liu & Yue Zhao & Chunfeng Lian & Zhongxiang Ding & Min Zhu & Dinggan, 2022. "A fully automatic AI system for tooth and alveolar bone segmentation from cone-beam CT images," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    19. Chowdhury, Emon Kalyan, 2019. "Use of Artificial Intelligence in Stock Trading," MPRA Paper 118175, University Library of Munich, Germany, revised 18 Apr 2019.
    20. Victor Olsavszky & Mihnea Dosius & Cristian Vladescu & Johannes Benecke, 2020. "Time Series Analysis and Forecasting with Automated Machine Learning on a National ICD-10 Database," IJERPH, MDPI, vol. 17(14), pages 1-17, July.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:1:p:480-:d:716349. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.